Boc-L-Valine (CAS 13734-41-3) Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Boc-L-Valine (CAS 13734-41-3) is a protected amino acid derivative widely used in peptide synthesis and pharmaceutical research.
Key Parameters
| Parameter | Specification |
|---|---|
| CAS Number | 13734-41-3 |
| Molecular Formula | C10H19NO4 |
| Purity | ≥98% (HPLC) |
| Storage | 2-8°C in dry conditions |
Competitive Comparison
| Feature | Boc-L-Valine | Fmoc-L-Valine |
|---|---|---|
| Acid Stability | High | Moderate |
| Deprotection Method | TFA | Piperidine |
2. Key Applications & Usage
Primary Applications
- Peptide synthesis (SPPS/Fmoc/Boc methodologies)
- Pharmaceutical intermediates for antiviral drugs
- Bioconjugation chemistry for antibody-drug conjugates
Handling Guidelines
- Use anhydrous solvents for dissolution (DCM/DMF recommended)
- Maintain inert atmosphere for oxygen-sensitive reactions
3. Step-by-Step Usage Examples
Case Study 1: Peptide Chain Elongation
- Activate Boc-L-Valine with HOBt/DIC in DMF (1:1:1 molar ratio)
- Couple to resin-bound peptide using double coupling protocol
- Deprotect with 30% TFA in DCM (2 × 5 min treatments)
4. Customer Success Stories
PharmaTech Solutions (Shanghai)
- Application: HCV protease inhibitor development
- Result: Achieved 92% coupling efficiency in solid-phase synthesis
BioConjugate Ltd. (Boston)
- Application: ADC linker development
- Result: Improved payload solubility by 40% vs. Fmoc-protected analogs
5. Technical Inquiry & Ordering
Contact our peptide chemistry specialists for technical support:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Why Choose Us?
- Batch-specific COA with HPLC/LCMS documentation
- Custom packaging (1g-25kg scale)



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