n-boc-d-proline cas 37784-17-1

Chemical Name:N-BOC-O-Benzyl-L-serine
CAS No.:23680-31-1Molecular Fomula:C15H21NO5
Molecular Weight:295.33
Appearance:White Powder
Assay: ≥98.00%

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N-Boc-D-Proline (CAS 37784-17-1) Ultimate User Guide

Table of Contents

1. Product Overview & Specifications

Parameter Specification
CAS Number 37784-17-1
Molecular Formula C₁₀H₁₇NO₄
Molecular Weight 215.25 g/mol
Appearance White crystalline powder
Purity ≥98% (HPLC)
Storage Conditions 2-8°C in dry environment
Optical Rotation [α]²⁰D = -75° to -85° (c=1 in CHCl₃)

2. Key Applications & Use Cases

2.1 Pharmaceutical Intermediate

Critical component in synthesizing chiral drugs including:

  • Antiviral protease inhibitors
  • Neurological disorder therapeutics
  • Oncology treatment candidates

2.2 Peptide Synthesis

Enables precise stereochemical control in:

  • Solid-phase peptide synthesis (SPPS)
  • Conformational restriction strategies
  • Bioactive peptide drug development

3. Industry Case Studies

Case Study 1: Anticancer Drug Development

Client: Top 10 Global Pharma Company

Application: Key intermediate in kinase inhibitor synthesis

Results: Achieved 99.2% enantiomeric excess (ee) in final API

Case Study 2: Antiviral Research

Client: European Research Consortium

Application: COVID-19 protease inhibitor lead optimization

Results: Improved compound bioavailability by 40%

4. Technical Parameter Comparison

Feature N-Boc-D-Proline Standard Proline L-Isomer
Chirality D-configuration Racemic L-configuration
Protection Group Boc None Boc
Solubility Improved in organic solvents Limited Similar to D-isomer

5. Procurement Guidance

Why Choose Us:

  • GMP-grade manufacturing facilities
  • Batch-to-batch consistency guaranteed
  • Global logistics support

Contact Our Experts:

Email: info@vivalr.com
Phone: (86) 15866781826

Request batch-specific COA or discuss custom synthesis options.

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