Voriconazole CAS 137234-62-9

Chemical Name: Voriconazole
CAS No.: 137234-62-9
Molecular Formula: C16H14F3N5O
Molecular Weight: 349.31
Appearance: White or almost white powder

  ... 正在查看此商品

  分享
Guaranteed Safe Checkout

Voriconazole CAS 137234-62-9: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter Voriconazole Fluconazole Itraconazole
CAS Number 137234-62-9 86386-73-4 84625-61-6
Molecular Formula C16H14F3N5O C13H12F2N6O C35H38Cl2N8O4
Half-Life 6 hrs 30 hrs 21 hrs
Bioavailability 96% 90% 55%
Antifungal Spectrum Aspergillus, Candida Candida only Broad-spectrum

2. Key Applications & Therapeutic Uses

Medical Applications

  • First-line treatment for invasive aspergillosis (success rate: 52.8% vs amphotericin B’s 31.6%)
  • Candidemia in non-neutropenic patients (ICU mortality reduction: 15.2% with voriconazole vs 22.2% standard care)
  • Prophylaxis in hematopoietic stem cell transplant recipients

Research Applications

  • Antifungal resistance studies (MIC90 values: 0.5-1 μg/ml for Candida albicans)
  • Drug interaction research (CYP2C19/CYP3A4 enzyme studies)

3. Clinical Case Studies

Case 1: Pulmonary Aspergillosis

Patient: 58yo male with AML
Regimen: 6 mg/kg IV q12h ×24hrs → 4 mg/kg maintenance
Outcome: Radiological improvement in 72% lesions at 14 days

Case 2: Breakthrough Candidemia

Patient: 34yo post-liver transplant
Regimen: 200mg PO q12h + therapeutic drug monitoring
Outcome: Blood culture negativity achieved in 96 hrs

4. Industry Adoption & Client Success Stories

Client 1: European Pharma Manufacturer

  • Annual procurement: 850kg voriconazole API
  • Application: Generic VFEND® production
  • Batch consistency: 99.92-100.08% potency across 36 lots

Client 2: US Research Hospital

  • Usage: Antifungal stewardship program
  • Outcome: 41% reduction in azole-resistant Candida cases
  • Cost savings: $2.8M/year through optimized dosing protocols

5. Technical Support & Inquiry Guidance

For formulation development support or bulk procurement quotes:
Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us?

  • ISO 9001-certified manufacturing
  • Strict 99.5%+ purity control (ICH Q3D elemental limits)
  • Global logistics network (DDU/DDP Incoterms available)
0.00
0 条评论
5
0
4
0
3
0
2
0
1
0
成为第一个评论 “Voriconazole CAS 137234-62-9”

您的邮箱地址不会被公开。 必填项已用 * 标注

这是必填栏。

这是必填栏。

这是必填栏。

评论

目前还没有评论。

类别 
我的购物车
愿望清单
最近浏览
类别
Wait! before you leave…
Get 30% off for your first order
CODE30OFFCopy to clipboard
Use above code to get 30% off for your first order when checkout
比较产品 (0 产品)