Bicine (CAS 150-25-4) Ultimate Guide 2025
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Bicine | Tris Buffer | HEPES |
|---|---|---|---|
| CAS Number | 150-25-4 | 77-86-1 | 7365-45-9 |
| pH Range | 7.6-9.0 | 7.0-9.0 | 6.8-8.2 |
| Temperature Stability | -20°C to 25°C | 4°C to 37°C | -80°C to 37°C |
| Metal Chelation | Low | Moderate | High |
2. Primary Applications in Life Sciences
- Protein crystallization studies
- Cell culture media additive
- PCR buffer component
- Electrophoresis running buffer
- Enzyme activity assays
3. Industry Implementation Cases
Pharmaceutical Research
XYZ Biotech achieved 23% higher protein yield using Bicine-based buffers in monoclonal antibody production compared to traditional phosphate buffers.
Diagnostic Kit Manufacturing
Leading IVD company reported 15-month stability in lateral flow assays when using Bicine as preservation buffer.
4. Buffer Selection Criteria
| Factor | Bicine Advantage |
|---|---|
| Low Toxicity | Non-teratogenic properties |
| Cost Efficiency | 40% lower than HEPES |
| Compatibility | Works with divalent cations |
5. Verified User Experiences
Case 1: Bioprocessing Facility
Challenge: Reduce endotoxin levels in vaccine production
Solution: Implemented 0.1M Bicine wash step
Result: 99.8% endotoxin reduction
Case 2: Academic Research Lab
Challenge: Maintain neuron viability in live imaging
Solution: Bicine-containing perfusion solution
Result: 72-hour cell viability achieved
6. Request Product Specifications
Contact our technical team for batch-specific COA:
Email: info@vivalr.com
Tel: (86) 15866781826
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