n-boc-O-benzyl-d-serine cas 47173-80-8

Table of Contents

• Product Overview & Specifications
• Applications & Detailed Uses
• Usage Guidelines
• Case Studies
• Client Examples
• Contact for Quotation

n-Boc-O-benzyl-D-serine (CAS 47173-80-8): Product Overview & Specifications

Key Specifications

Comparative Analysis

Applications & Detailed Uses

Primary Applications

• Peptide synthesis (orthogonal protection strategy)
• Pharmaceutical intermediates for kinase inhibitors
• Glycopeptide antibiotic research
• Chiral building blocks in asymmetric synthesis

Industry-Specific Uses

• Oncology Research: Key intermediate for PARP inhibitors
• Antiviral Drugs: Used in HIV protease inhibitor development
• Neurological Studies: NMDA receptor modulation research

Usage Guidelines

Recommended Protocols

1. Deprotection: Use TFA for Boc removal (1-2h at 0°C)
2. Coupling: Employ HOBt/DIC in DMF at -20°C
3. Storage: Maintain nitrogen atmosphere for long-term storage

Safety Considerations

• Use PPE (gloves, goggles) during handling
• Avoid strong oxidizing agents
• Store separately from bases

Case Studies

Case 1: Peptide Drug Development

Challenge: Low yield (32%) in solid-phase synthesis
Solution: Implemented orthogonal protection strategy using n-Boc-O-benzyl-D-serine
Outcome: Yield improved to 78% with 99% enantiomeric excess

Case 2: Antibiotic Research

Challenge: Glycosylation inefficiency in vancomycin analogs
Solution: Utilized benzyl protection for selective OH group activation
Result: Achieved 92% glycosylation efficiency

Client Examples

Pharmaceutical Company A (Top 10 Global)

• Application: PARP inhibitor intermediate
• Order History: 50kg/year since 2022
• Purity Requirement: ≥99% (custom synthesis)

Research Institute B (EU-based)

• Usage: Neurological disorder studies
• Publication: 3 papers using this compound
• Feedback: Cited 98% batch consistency

Contact for Quotation

Request custom synthesis options or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us?

• GMP-certified production facilities
• ISO 9001:2015 quality management
• 24/7 technical support team