Trimethoprim CAS 738-70-5

Chemical Name: Trimethoprim/ TMP
CAS No.: 738-70-5
Molecular Formula: C14H18N4O3
Molecular Weight: 290.32
Appearance: White or yellowish-white powder
Grade: BP2018

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Trimethoprim (CAS 738-70-5): Comprehensive Product Guide

1. Product Overview & Specifications

Basic Information

Parameter Details
CAS Number 738-70-5
Molecular Formula C14H18N4O3
Molecular Weight 290.32 g/mol
Appearance White to off-white crystalline powder
Melting Point 199–203°C
Solubility Soluble in DMSO, chloroform; slightly soluble in ethanol; insoluble in water
Storage 2–8°C, protected from light

2. Key Applications

Pharmaceutical Industry

Trimethoprim is widely used as an antibacterial synergist, enhancing the efficacy of sulfonamide antibiotics in treating urinary tract infections, respiratory infections, and gastrointestinal disorders.

Veterinary Medicine

In animal health, it serves as a critical component in combating bacterial infections and coccidiosis in livestock, poultry, and aquaculture.

Research & Development

As a reference standard (HPLC ≥98%), it supports drug discovery, pharmacokinetic studies, and quality control in laboratories.

3. Usage Scenarios

Human Therapeutics

Combined with sulfamethoxazole, Trimethoprim forms co-trimoxazole, a first-line treatment for Pneumocystis pneumonia in immunocompromised patients.

Poultry Farming

At 0.02–0.04% concentration in feed, it prevents outbreaks of E. coli and Salmonella, improving livestock survival rates.

4. Customer Case Studies

Case 1: Pharmaceutical Manufacturer (Hubei, China)

A leading API producer uses Trimethoprim (99% purity) to formulate combination therapies, achieving 30% faster production cycles through optimized solubility profiles.

Case 2: Veterinary Research Institute (Shanghai)

Researchers reduced poultry mortality by 45% using Trimethoprim-supplemented feed, validated through a 12-month trial across 10,000 birds.

5. Inquiry & Contact

Customized solutions available: Bulk quantities (25 kg drums), HPLC-grade standards, and veterinary formulations.

Contact Method Details
Email info@vivalr.com
Phone (86) 15866781826

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