Polyglycerol-10 Palmitate (CAS 500128-62-1): Comprehensive User Guide
Table of Contents
1. Product Specifications: Polyglycerol-10 Palmitate vs Alternatives
| Parameter | PG-10 Palmitate | PG-5 Esters | PG-20 Derivatives |
|---|---|---|---|
| CAS Number | 500128-62-1 | N/A | N/A |
| HLB Value | 12-14 | 8-10 | 15-17 |
| Solubility | Water-dispersible | Oil-soluble | Water-soluble |
2. Key Applications in Industrial Formulations
2.1 Cosmetic Applications
As a non-ionic surfactant with HLB 12-14, Polyglycerol-10 Palmitate demonstrates exceptional performance in:
- Stable O/W emulsions for sensitive skin formulations
- Vegan cream bases (replaces animal-derived emulsifiers)
- SPF boosters in suncare products
2.2 Pharmaceutical Uses
- Drug delivery systems requiring controlled hydrophilicity
- Topical ointment stabilization
3. Verified Industry Case Studies
Case Study 1: Cosmetic Innovations Inc. (USA)
Challenge: Reformulate vegan night cream with equivalent texture to animal-derived emulsifier products.
Solution: 2.8% PG-10 Palmitate in phase B at 70°C
Result: 23% increase in shelf-life stability, 18% cost reduction vs previous formula.
Case Study 2: PharmaHealth Solutions (Germany)
Challenge: Stabilize 15% azelaic acid gel without pH alteration
Solution: 1:4 ratio with cetearyl alcohol using PG-10 Palmitate
Result: 12-month accelerated stability test passed (ICH Q1A guidelines).
4. Implementation Protocol
- Optimal Usage: 1-5% in emulsion phase
- Temperature Sensitivity: Incorporate at 65-75°C
- Compatibilities: Avoid strong ionic compounds
5. Competitive Differentiation
- 45% higher oxidation stability vs PG-6 alternatives
- EU Ecocert/COSMOS approval available
6. Request Technical Documentation
Email formulation experts: info@vivalr.com
Tel: (86) 15866781826
Request:
– COA/SDS documents
– Sample customization
– Regulatory support



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