Comprehensive Guide to Sodium 1-Palmitoyl-L-Prolinate (CAS 58725-33-0)
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 58725-33-0 |
| Molecular Formula | C21H38NNaO3 |
| Molecular Weight | 399.52 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Solubility | Water-soluble (50 mg/mL at 25°C) |
| Storage | 2-8°C in airtight container |
2. Key Applications & Industrial Uses
2.1 Cosmetic Formulations
• Mild surfactant in facial cleansers & makeup removers
• Stabilizing agent in emulsion systems
• Penetration enhancer for active ingredients
2.2 Pharmaceutical Development
• Drug delivery matrix component
• Bioavailability improvement agent
• Transdermal formulation excipient
2.3 Biochemical Research
• Membrane protein studies
• Lipid bilayer modeling
• Cell culture applications
3. Performance Comparison Analysis
| Feature | Standard Grade | Pharma Grade |
|---|---|---|
| Purity | 98% | 99.5% |
| Endotoxin Level | <50 EU/mg | <5 EU/mg |
| Heavy Metals | <10 ppm | <2 ppm |
| Certification | Technical Data Sheet | GMP Compliance |
4. Usage Guidelines by Industry
4.1 Skincare Product Development
Recommended dosage: 0.5-2% w/w
Compatibility: Stable with pH 5-8 formulations
Processing: Add during emulsion phase at 40-45°C
4.2 Transdermal Patch Manufacturing
Optimal concentration: 1.5-3% in matrix
Temperature sensitivity: Avoid >60°C processing
Storage requirements: Dry nitrogen environment
5. Real-World Implementation Cases
Case 1: Evelyn Cosmetics (France)
• Application: pH-balanced cleansing emulsion
• Formulation: 1.2% Sodium 1-Palmitoyl-L-Prolinate
• Result: 40% reduction in skin irritation vs SLES-based formulas
Case 2: PharmaBio Solutions (USA)
• Application: NSAID topical gel
• Outcome: 3.2x bioavailability improvement
• Production Scale: 800 kg/month
Case 3: Cambridge University Research
• Study: Lipid nanoparticle delivery systems
• Finding: Enhanced cellular uptake by 67%
• Publication: J. Controlled Release (2023)
6. Technical Consultation & Ordering
Contact our technical team for:
• Custom formulation support
• Bulk pricing (25kg+ quantities)
• Regulatory documentation
Email: info@vivalr.com
Tel: (86) 15866781826



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