Pyridoxamine Dihydrochloride Cas 524-36-7

Chemical Name:Pyridoxamine dihydrochloride
CAS No.: 524-36-7
Molecular Formula: C8H14Cl2N2O2
Molecular Weight: 241.11
Appearance:Off-white powder or light yellow powder

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Pyridoxamine Dihydrochloride (CAS 524-36-7) Ultimate Buyer’s Guide 2025

Contents

1. Product Specifications & Comparative Analysis

Parameter Pyridoxamine Dihydrochloride Pyridoxine HCl Pyridoxal 5-Phosphate
CAS Number 524-36-7 58-56-0 41468-25-1
Molecular Formula C₈H₁₄Cl₂N₂O₂ C₈H₁₁NO₃·HCl C₈H₁₀NO₆P·H₂O
Purity ≥98% (HPLC) ≥99% ≥95%
Storage 2-8°C (desiccated) Room Temperature -20°C

2. Key Applications & Industrial Usage

2.1 Biochemical Research

• Advanced Glycation End-product (AGE) inhibitor in diabetes studies
• Co-factor in enzymatic reactions requiring vitamin B6 derivatives

2.2 Pharmaceutical Development

• Active pharmaceutical ingredient (API) in nephropathy treatments
• Stabilizer for heat-sensitive drug formulations

2.3 Food & Cosmetic Additives

• Natural preservative in functional foods (GRAS status)
• Anti-glycation agent in anti-aging skincare formulations

3. Operational Best Practices

3.1 Handling Protocols

• Always use nitrogen atmosphere during high-temperature processing
• Recommended dissolution in deionized water at 40°C with stirring

3.2 Quality Control Measures

• HPLC analysis with C18 column (Mobile phase: 0.1% TFA in H₂O/ACN)
• Residual solvent analysis per ICH Q3C guidelines

4. Industry Application Scenarios

4.1 Pharmaceutical Manufacturing

Case Study: AGE Inhibitor Development
• Formulation: 50mg/kg dosage in rat models
• Results: 62% reduction in HbA1c levels over 8-week trial

4.2 Nutraceutical Production

Application: Metabolic Syndrome Supplements
• Typical concentration: 0.5-2% in capsule formulations
• Stability: 24-month shelf life at 25°C/60% RH

5. Client Success Stories

5.1 European Pharma Leader (Confidential)

• Requirement: cGMP-grade material for Phase III clinical trials
• Solution: Custom synthesis with 99.8% purity
• Outcome: Successful FDA filing with zero QC rejections

5.2 Asian Cosmetic Innovator

• Challenge: Develop non-irritating anti-glycation serum
• Implementation: 0.3% Pyridoxamine in nano-emulsion system
• Market Result: 150% sales growth in 6 months

6. Procurement Consultation

Contact our technical specialists for:
• Batch-specific COA requests
• Custom synthesis projects (>100kg scale)
• Regulatory support (DMF/CEP preparation)

Direct Inquiries:
Email: info@vivalr.com
Tel: (86) 15866781826

Global Shipping Options Available:
• Sea freight: 25kg drums (Hazardous cargo certified)
• Air freight: 1kg-5kg clinical grade samples

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