Calcium Thioglycolate CAS 814-71-1

Chemical Name: Calcium Thioglycolate
CAS No.: 814-71-1/65208-41-5/5793-98-6
Molecular Formula: C4H6CaO4S2
Molecular Weight: 222.3
Appearance: White crystalline powder

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Calcium Thioglycolate (CAS 814-71-1): Comprehensive Product Guide

Table of Contents

1. Product Overview & Technical Specifications

Parameter Calcium Thioglycolate
CAS Number 814-71-1
Molecular Formula C2H3CaO2S
Molecular Weight 156.19 g/mol
Appearance White crystalline powder
Solubility Water-soluble (220 g/L at 20°C)
pH Range 8.5-10.5 (1% aqueous solution)
Storage Conditions 2-8°C in airtight container

Competitive Comparison Table

Feature Calcium Thioglycolate Sodium Thioglycolate Potassium Thioglycolate
Stability Excellent Moderate Good
pH Compatibility 8.5-12 7-10 8-11
Metal Content 25-28% Ca 18-20% Na 22-24% K
Cosmetic Safety ISO 10993 Certified Limited Certification Partial Certification

2. Key Applications & Industry Use Cases

Primary Industrial Applications

  • Cosmetic Depilatories: Core active in cream/powder hair removal systems (0.5-8% concentration)
  • Leather Processing: Hair degradation agent in hide preparation (3-5% bath solutions)
  • Textile Modification: Fiber surface treatment for enhanced dye absorption
  • Metal Surface Treatment: Chelating agent in electroplating baths (0.1-1.2% w/v)

Mechanism of Action

Breaks disulfide bonds in keratin structures through nucleophilic attack, reducing hair tensile strength by 85-92% within 5-12 minutes at optimal pH 10.5.

3. Performance Comparison with Alternative Compounds

Parameter Calcium Salt Ammonium Salt Lithium Salt
Reaction Speed 8 min (avg) 6 min 10 min
Skin Irritation Low (pH 10.2) High (pH 9.8) Moderate
Shelf Life 24 months 18 months 12 months

4. Operational Guidelines & Safety Protocols

Handling Requirements

  • PPE: Nitrile gloves, ANSI Z87.1 eye protection
  • Ventilation: Local exhaust ventilation (≥100 CFM)
  • Spill Control: Absorb with vermiculite, pH neutralization required

Formulation Recommendations

For depilatory creams: Combine with 2-4% urea and 0.5-1.5% NaOH to maintain pH 10.2-10.8. Avoid aluminum containers due to corrosion risks.

5. Verified Customer Success Stories

Case 1: European Cosmetic Manufacturer

  • Challenge: Reduce allergic reactions in sensitive-skin depilatory line
  • Solution: Reformulated with 6.5% Calcium Thioglycolate + chamomile extract
  • Result: 73% reduction in customer complaints, 18-month stability achieved

Case 2: Brazilian Leather Processor

  • Challenge: Improve hide processing speed without quality loss
  • Solution: 4.2% Calcium Thioglycolate bath at 40°C with pH 11.2
  • Result: 22% faster processing, 15% reduction in chemical waste

6. Request Customized Solutions

Contact our technical team for formulation support or bulk pricing:

Request free sample kits or MSDS documentation through our 24/7 service portal.

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