5-mercapto-1-methyltetrazole cas 13183-79-4

Assay:  99.0%
Appearance: White powder
Package: Net weight 25kg/drum
Sample: Available

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5-Mercapto-1-methyltetrazole (CAS 13183-79-4) Comprehensive Technical Guide

1. Product Specifications & Comparative Analysis

Parameter Specification
Chemical Formula C2H4N4S
Molecular Weight 116.15 g/mol
Appearance White to pale yellow crystalline powder
Melting Point 124-126°C
Purity Grade Pharmaceutical Intermediate (≥99%)
Storage Conditions Room temperature, moisture-proof

2. Functional Applications

This heterocyclic compound serves as critical intermediate in:

  • Cephalosporin antibiotic synthesis (Cefoperazone, Cefotetan, Cefamandole)
  • Pharmaceutical impurity reference standards
  • Specialty chemical synthesis
  • Coordination chemistry applications

3. Operational Guidelines

Handling Protocols:

  • Use PPE including nitrile gloves and safety goggles
  • Maintain pH between 6.5-7.5 in aqueous solutions
  • Store in sealed containers under nitrogen atmosphere

Reaction Optimization:

  • Optimal reaction temperature: 40-50°C
  • Recommended solvent systems: DMF/DMSO
  • Stoichiometric ratios: 1:1.05 molar excess for nucleophilic substitutions

4. Implementation Case Studies

Case 1: Cefoperazone Sodium Production

  • Yield improvement from 68% to 82% through optimized coupling conditions
  • Reduced reaction time by 30% using catalytic phase transfer

5. Client Success Stories

Pharmaceutical Manufacturer A:

  • Achieved 99.3% HPLC purity in final API
  • Reduced production costs by 18% through process intensification

Chemical Supplier B:

  • Scaled production to metric ton scale with 99.5% consistency
  • Implemented closed-loop solvent recovery system

6. Technical Consultation

For formulation support, bulk pricing, or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826

Our technical team provides:

  • Process validation support
  • Regulatory documentation
  • Custom purity specifications

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