5-Mercapto-1-methyltetrazole (CAS 13183-79-4) Comprehensive Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Specification |
|---|---|
| Chemical Formula | C2H4N4S |
| Molecular Weight | 116.15 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Melting Point | 124-126°C |
| Purity Grade | Pharmaceutical Intermediate (≥99%) |
| Storage Conditions | Room temperature, moisture-proof |
2. Functional Applications
This heterocyclic compound serves as critical intermediate in:
- Cephalosporin antibiotic synthesis (Cefoperazone, Cefotetan, Cefamandole)
- Pharmaceutical impurity reference standards
- Specialty chemical synthesis
- Coordination chemistry applications
3. Operational Guidelines
Handling Protocols:
- Use PPE including nitrile gloves and safety goggles
- Maintain pH between 6.5-7.5 in aqueous solutions
- Store in sealed containers under nitrogen atmosphere
Reaction Optimization:
- Optimal reaction temperature: 40-50°C
- Recommended solvent systems: DMF/DMSO
- Stoichiometric ratios: 1:1.05 molar excess for nucleophilic substitutions
4. Implementation Case Studies
Case 1: Cefoperazone Sodium Production
- Yield improvement from 68% to 82% through optimized coupling conditions
- Reduced reaction time by 30% using catalytic phase transfer
5. Client Success Stories
Pharmaceutical Manufacturer A:
- Achieved 99.3% HPLC purity in final API
- Reduced production costs by 18% through process intensification
Chemical Supplier B:
- Scaled production to metric ton scale with 99.5% consistency
- Implemented closed-loop solvent recovery system
6. Technical Consultation
For formulation support, bulk pricing, or custom synthesis requirements:
Email: info@vivalr.com
Tel: (86) 15866781826
Our technical team provides:
- Process validation support
- Regulatory documentation
- Custom purity specifications



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