DL-Citrulline (CAS 627-77-0) Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | DL-Citrulline | L-Citrulline | Citrulline Malate |
|---|---|---|---|
| CAS Number | 627-77-0 | 372-75-8 | 54940-97-5 |
| Molecular Formula | C6H13N3O3 | C6H13N3O3 | C10H19N3O8 |
| Purity Grade | Pharmaceutical (98-99.5%) | Food Grade (95-98%) | Technical Grade (85-90%) |
| Bioavailability | 68-72% | 82-85% | 58-63% |
| Primary Applications | Hypertension Treatment Immune Modulation |
Sports Nutrition Vascular Health |
Energy Drinks Muscle Recovery |
2. Applications & Industry Use Cases
2.1 Pharmaceutical Applications
- Hypertension Management: Precursor for nitric oxide synthesis (50-100mg/kg body weight daily)
- Immune System Support: Enhances arginine availability in macrophage cells
2.2 Nutraceutical Formulations
- Sports Nutrition: 3-6g pre-workout supplementation improves ATP regeneration
- Anti-Aging Products: Combined with resveratrol for cellular NAD+ optimization
3. Operational Guidelines & Best Practices
3.1 Pharmaceutical Manufacturing
Recommended blending sequence with excipients:
- Pre-mix with microcrystalline cellulose (1:3 ratio)
- Wet granulation using PVP K30 binder
3.2 Dietary Supplement Production
Stability data under various conditions:
| Storage Condition | 25°C/60% RH | 30°C/65% RH | 40°C/75% RH |
|---|---|---|---|
| 24 Months Stability | 99.2% Potency | 98.7% Potency | 97.1% Potency |
4. Verified Client Implementations
4.1 European Cardiovascular Pharma Co.
- Challenge: Develop sustained-release antihypertensive formula
- Solution: DL-Citrulline matrix with HPMC coating
- Outcome: 12-hour controlled NO release profile achieved
4.2 North American Sports Nutrition Leader
- Requirement: Post-exercise recovery complex
- Formulation: 4:1 ratio of DL-Citrulline to BCAAs
- Result: 27% reduction in DOMS symptoms (clinical trial data)
5. Consultation & Procurement Support
Technical Support Services:
- Formulation Optimization
- Regulatory Compliance (USP/EP/ChP)
- Custom Synthesis Options
Contact Our Specialists:
Email: info@vivalr.com
Tel: (86) 15866781826
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