Methyl 4-formylbenzoate CAS 1571-08-0

Chemical Name: Methyl 4-formylbenzoate
CAS No.: 1571-08-0
Molecular Fomula: C9H8O3
Molecular Weight: 164.16
Appearance: Off-White crystal

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Methyl 4-formylbenzoate CAS 1571-08-0: Ultimate Buyer’s Guide (2024)

Table of Contents

1. Product Overview & Specifications

Methyl 4-formylbenzoate (CAS 1571-08-0) is a specialty aromatic ester with molecular formula C9H8O3. Key parameters:

Parameter Specification
Molecular Weight 164.16 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Melting Point 72-75°C
Storage 2-8°C in airtight container

2. Key Applications & Industrial Uses

Primary industrial applications include:

  • Pharmaceutical Intermediate: Synthesis of COX-2 inhibitors and antiretroviral drugs
  • Organic Synthesis: Building block for Schiff base ligands and metal-organic frameworks
  • Flavor/Fragrance: Precursor for musk-type aromatic compounds
  • Polymer Chemistry: Monomer for specialty polyesters

3. Technical Comparison with Alternatives

Compound Methyl 4-formylbenzoate Ethyl 4-formylbenzoate Methyl benzoate
Reactivity High (dual functional groups) Moderate Low
Thermal Stability Up to 200°C 185°C 150°C
Pharma Compatibility USP Grade Available Industrial Grade Not Applicable

4. Operational Best Practices

  • Use nitrogen blanket during high-temperature reactions
  • Maintain pH 6-8 in aqueous solutions
  • Implement cold trap systems for vapor handling
  • Recommended solvent: Anhydrous DMF or THF

5. Verified Client Success Stories

Case 1: Top 10 Pharma Company (EU)

  • Application: HIV protease inhibitor intermediate
  • Result: 22% yield improvement vs. previous synthesis route
  • Scale: 800kg/month production

Case 2: Specialty Chemical Manufacturer (USA)

  • Application: Liquid crystal monomer synthesis
  • Result: Achieved 99.5% enantiomeric purity
  • Scale: 2MT quarterly procurement

6. Request Customized Solution

Contact our technical team for:

  • Bulk pricing (100kg+ orders)
  • Custom synthesis specifications
  • Regulatory support (REACH, FDA DMF)

Email: info@vivalr.com
Tel: (86) 15866781826

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