2,3-Dibromothiophene

2,3-Dibromothiophene User Guide

Table of Contents

• 1. Product Specifications & Comparative Analysis
• 2. Key Applications & Industrial Uses
• 3. Operational Guidelines & Best Practices
• 4. Application Case Studies
• 5. Verified Client Implementations
• 6. Request Customized Quotation

1. Product Specifications & Comparative Analysis

2. Key Applications & Industrial Uses

Core Functional Properties:

• Electrophilic aromatic substitution precursor
• Cross-coupling reaction facilitator (Suzuki, Stille)
• Conjugated polymer building block

Industrial Applications:

• Pharmaceutical Intermediates: Synthesis of tyrosine kinase inhibitors
• OLED Materials: Electron-transport layer components
• Agrochemicals: Thiophene-based pesticide development
• Organic Semiconductors: π-conjugated system construction

3. Operational Guidelines & Best Practices

Handling Protocols:

• Maintain inert atmosphere (N₂/Ar) during reactions
• Use anhydrous solvents (THF, DCM) for optimal reactivity
• Recommended stoichiometry: 1.1-1.3 eq in coupling reactions

Safety Measures:

• PPE Requirements: Nitrile gloves, chemical goggles
• Storage: 2-8°C in amber glass containers
• Shelf Life: 24 months under proper conditions

4. Application Case Studies

Case 1: OLED Material Synthesis

Objective: Develop blue-emitting layer for flexible displays
Process: Suzuki-Miyaura coupling with 2,3-dibromothiophene (82% yield)
Outcome: Achieved 18% external quantum efficiency

Case 2: Anticancer Drug Intermediate

Objective: Create EGFR inhibitor core structure
Process: Buchwald-Hartwig amination (0.5 mol% catalyst loading)
Outcome: 92% purity in final API intermediate

5. Verified Client Implementations

Client A: Global Pharma Leader

Application: Kinase inhibitor R&D
Volume: 150kg annual procurement
Result: Reduced synthesis steps from 7 to 4 stages

Client B: OLED Manufacturer

Application: Flexible display production
Specification: ≥99.5% HPLC purity
Impact: 22% reduction in production costs

6. Request Customized Quotation

Contact our technical specialists for:
– Bulk pricing (100g to ton-scale)
– Custom purity specifications (98%-99.9%)
– Technical documentation (COA, MSDS)
Email: info@vivalr.com
Tel: (86) 15866781826