4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride (CAS 59703-00-3) User Guide
Table of Contents
1. Product Overview & Specifications
CAS No.: 59703-00-3
Molecular Formula: C₇H₉ClN₂O₃
Molecular Weight: 216.61 g/mol
Appearance: White to off-white crystalline powder
Purity: ≥98% (HPLC)
Storage: 2-8°C in a dry, airtight container
Comparative Analysis
| Parameter | 4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride | Similar Derivatives |
|---|---|---|
| Reactivity | High (due to carbonyl chloride group) | Moderate (ester derivatives) |
| Stability | Stable under inert conditions | Moisture-sensitive |
| Pharma Applications | Widely used in API synthesis | Limited to niche processes |
2. Applications & Use Cases
This compound is a critical intermediate in:
- Pharmaceuticals: Synthesis of cephalosporin antibiotics (e.g., cefpirome).
- Peptide Chemistry: Activation of carboxyl groups for peptide coupling.
- Organic Synthesis: Building block for heterocyclic compounds.
Key Reactions
- Nucleophilic acyl substitution for amide bond formation
- Ring-opening reactions in piperazine-based drug design
3. Case Studies
Case 1: Antibiotic Intermediate Synthesis
A European pharma company achieved 92% yield in cefpodoxime proxetil synthesis using this reagent, reducing side reactions by 40% compared to traditional methods.
Case 2: Peptide Drug Development
Used in solid-phase synthesis of anti-inflammatory peptides, enabling precise control over stereochemistry at scale.
4. Client Success Stories
Client A: Top-10 Global Pharma Company
Integrated the compound into their β-lactam antibiotic production line, reducing purification steps by 3 stages.
Client B: Specialty Chemical Manufacturer
Developed novel kinase inhibitors using this reagent, accelerating preclinical trials by 8 months.
5. Inquiry & Contact
Request pricing, COA, or bulk quotes:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Why Choose Us?
– ISO-certified production
– 24/7 technical support
– Global logistics network
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