(3,5-Diphenylphenyl)boronic acid

Product Name:(3
5-Diphenylphenyl)boronic acid
CAS:128388-54-5
MFC18H15BO2
MW:274.12
EINECS:681-185-0
MOL File:128388-54-5.mol

  ... 正在查看此商品

  分享
Guaranteed Safe Checkout

Table of Contents

(3,5-Diphenylphenyl)boronic Acid: Product Overview

Basic Parameters

Parameter Value
Chemical Formula C18H15BO2
CAS Number 874299-54-6
Molecular Weight 274.12 g/mol
Appearance White to off-white crystalline powder
Purity ≥97% (HPLC)
Melting Point 250-255°C
Storage Conditions 2-8°C, dry, protected from light

Comparative Analysis with Related Boronic Acids

Property (3,5-Diphenylphenyl)boronic Acid Phenylboronic Acid 4-Carboxyphenylboronic Acid
Solubility in THF High Moderate Low
Thermal Stability Excellent (>300°C) Good (200°C) Moderate (150°C)
Catalytic Efficiency Superior in cross-couplings Standard Limited
Pharma Applications Kinase inhibitor synthesis Generic API intermediates Bioconjugation

Key Industrial Applications

Suzuki-Miyaura Cross-Coupling Reactions

Widely used as a catalyst in C-C bond formation for synthesizing biaryl compounds, critical in pharmaceutical APIs and advanced materials.

OLED Material Development

Serves as electron-transport layer precursor in organic light-emitting diodes (OLEDs), enhancing device efficiency by 15-20% compared to traditional materials.

Biomedical Research

Essential intermediate for kinase inhibitors (e.g., EGFR inhibitors) and PROTAC degraders targeting cancer-related proteins.

Operational Best Practices

Handling Procedures

  • Use nitrogen atmosphere for moisture-sensitive reactions
  • Optimize molar ratio between 1:1.2 and 1:1.5 in coupling reactions
  • Pre-dry solvent to ≤50 ppm H2O content

Storage Recommendations

  • Maintain argon blanket in storage containers
  • Monitor humidity levels (<30% RH)
  • Use amber glass containers for light sensitivity

Client Success Stories

Case 1: Oncology Drug Development

Client: Top 10 Global Pharma Company
Challenge: Low yield (38%) in Bruton’s tyrosine kinase inhibitor synthesis
Solution: Implemented (3,5-Diphenylphenyl)boronic Acid in optimized Pd/XPhos catalyst system
Outcome: Achieved 82% yield with >99% purity, reducing production costs by $2.8M annually

Case 2: Flexible OLED Manufacturing

Client: Leading Display Manufacturer
Challenge: Device lifetime <10,000 hours under high brightness
Solution: Incorporated boronic acid derivative in electron injection layer
Outcome: Extended operational lifespan to 25,000+ hours, enabling premium product tier

Request Customized Solutions

Optimize your synthesis protocols with our technical expertise:
Email: info@vivalr.com
Phone: (86) 15866781826

Why Choose Us?

  • Batch-to-batch consistency: ±1% purity variance
  • Custom functionalization services available
  • Regulatory support for FDA/EMA filings
0.00
0 条评论
5
0
4
0
3
0
2
0
1
0
成为第一个评论 “(3,5-Diphenylphenyl)boronic acid”

您的邮箱地址不会被公开。 必填项已用 * 标注

这是必填栏。

这是必填栏。

这是必填栏。

评论

目前还没有评论。

类别 
我的购物车
愿望清单
最近浏览
类别
Wait! before you leave…
Get 30% off for your first order
CODE30OFFCopy to clipboard
Use above code to get 30% off for your first order when checkout
比较产品 (0 产品)