(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

Product Name：(5R-cis)-Toluene-4-sulfonic acid 5-(2
4-difluorophenyl)-5-(1H-1
2
4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
CAS：149809-43-8
MFC21H21F2N3O4S
MW：449.47
EINECS：1308068-626-2
MOL File：149809-43-8.mol

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Technical Guide: (5R-cis)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-(1H-1,2,4-Triazol-1-yl)methyltetrahydrofuran-3-ylmethyl Ester

1. Product Overview & Specifications
2. Key Applications
3. Usage Guidelines
4. Industrial Case Studies
5. Client Success Stories
6. Request a Quote

1. Product Overview & Specifications

CAS No.: 149809-43-8

Molecular Formula: C₂₁H₂₁F₂N₃O₄S

Molecular Weight: 449.47 g/mol

Key Features:

High-purity intermediate for antifungal drug synthesis
Stable under controlled storage conditions
Critical component in posaconazole production

Comparative Analysis
Parameter	This Product	Generic Alternatives
Purity	≥98%	90-95%
Synthesis Efficiency	Optimized reaction pathways	Standard protocols

2. Key Applications

This compound serves as:

Primary intermediate in posaconazole API manufacturing
Core building block for triazole-containing antifungals
Research chemical for novel antifungal development

3. Usage Guidelines

Recommended Workflow:

Storage: Maintain at 2-8°C in sealed containers
Handling: Use inert atmosphere for sensitive reactions
Reaction Optimization: Typical yield 72-85% in coupling steps

4. Industrial Case Studies

Case 1: Large-Scale API Production

Challenge: Scaling from lab to 500kg batch production
Solution: Optimized crystallization parameters achieving 98.2% purity

5. Client Success Stories

Jiangsu Keben Pharmaceuticals

Achieved 22% cost reduction in posaconazole synthesis through improved intermediate utilization.

Nanjing Shizhou Biotechnology

Reduced production cycle time by 18% using optimized catalytic systems.

6. Request a Quote

Contact our technical team for customized solutions:

Email: info@vivalr.com
Tel: (86) 15866781826

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(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

Technical Guide: (5R-cis)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-(1H-1,2,4-Triazol-1-yl)methyltetrahydrofuran-3-ylmethyl Ester

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