2-Methoxy-5-pyridineboronic Acid: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Usage Guidelines & Best Practices
- 4. Comparative Analysis with Alternative Boronic Acids
- 5. Real-World Application Case Studies
- 6. Technical Inquiry & Ordering Information
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 374545-67-8 |
| Molecular Formula | C6H8BNO3 |
| Purity | ≥97% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Storage Temperature | 2-8°C under inert atmosphere |
2. Key Applications & Industrial Uses
This boronic acid derivative is particularly valuable in:
- Suzuki-Miyaura cross-coupling reactions for pharmaceutical intermediates
- Construction of complex heterocyclic compounds
- Development of kinase inhibitors in cancer research
- Material science applications for organic electronic components
3. Usage Guidelines & Best Practices
Optimal Reaction Conditions:
| Parameter | Recommended Range |
|---|---|
| Solvent System | DME/H2O (3:1 v/v) |
| Catalyst | Pd(PPh3)4 (1-3 mol%) |
| Temperature | 80-100°C |
| Reaction Time | 12-24 hours |
4. Comparative Analysis with Alternative Boronic Acids
| Property | 2-Methoxy-5-pyridine | Phenylboronic Acid | Thiophene-2-boronic Acid |
|---|---|---|---|
| Water Solubility | Low | Moderate | Very Low |
| Coupling Efficiency | 92-95% | 85-88% | 78-82% |
| Thermal Stability | Excellent | Good | Moderate |
5. Real-World Application Case Studies
Case Study 1: Pharmaceutical Intermediate Synthesis
Client: Top 10 Global Pharma Company
Application: Production of tyrosine kinase inhibitor intermediate
Result: Achieved 94% yield in large-scale coupling reaction (500kg batch)
Case Study 2: OLED Material Development
Client: Leading Display Manufacturer
Application: Synthesis of electron-transport layer molecules
Result: Improved device efficiency by 18% compared to previous formulations
6. Technical Inquiry & Ordering Information
For technical specifications, custom synthesis requirements, or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
Our technical team can provide:
- Custom purity specifications (up to 99.9%)
- GMP-grade manufacturing options
- Stability data and regulatory support
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