1. Product Overview and Specifications

Comparative Analysis: Compared to similar pyridine derivatives (e.g., 2-amino-5-chloropyridine-3-carbaldehyde), this compound offers superior reactivity in nucleophilic substitutions due to its unsubstituted aldehyde group.

2. Key Applications and Industrial Uses

• Pharmaceutical Intermediates: Critical precursor for antiretroviral drugs (e.g., Nevirapine analogs)
• Agrochemicals: Building block for pyrethroid insecticides
• Coordination Chemistry: Ligand synthesis for transition metal catalysts
• Material Science: Functional monomer in conductive polymer research

3. Synthesis and Chemical Properties

Synthetic Routes:
– Vilsmeier-Haack formulation of 3-amino-pyridine derivatives
– Catalytic oxidation of 2-amino-3-hydroxymethylpyridine
Typical yield: 68-75% (optimized conditions)

4. Safety and Handling Guidelines

5. Client Case Studies

Case 1: Antiviral Drug Development

Client: European Pharma Research Consortium
Application: Synthesis of NNRTI candidates (IC₅₀ improvement ≥40% vs. baseline)

Case 2: Specialty Catalyst Production

Client: Japan Advanced Materials Co., Ltd.
Application: Development of Pd-based cross-coupling catalysts (TON increased to 12,500)

6. Request Customized Solutions

For technical specifications, bulk pricing, or custom synthesis:
Email: info@vivalr.com
Tel: (86) 15866781826