5-Methyl-2-thiophenecarboxylic Acid: Technical Guide & Applications
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industry Use Cases
- 3. Comparative Analysis with Alternatives
- 4. Customer Success Stories
- 5. Procurement Guidance
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 4282-34-2 |
| Molecular Formula | C7H6O2S |
| Molecular Weight | 154.19 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥98% |
| Melting Point | 145-148°C |
| Solubility | Soluble in DMSO, methanol; slightly soluble in water |
2. Key Applications & Industry Use Cases
Pharmaceutical Intermediate
Widely used in synthesis of:
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Antimicrobial agents
- Kinase inhibitors for cancer therapy
Agrochemical Synthesis
Key component in:
- Herbicide formulations
- Fungicide precursors
- Plant growth regulators
Material Science
- Conductive polymer production
- OLED material development
3. Comparative Analysis with Alternatives
| Feature | 5-Methyl-2-thiophenecarboxylic Acid | Thiophene-2-carboxylic Acid | 5-Bromo-2-thiophenecarboxylic Acid |
|---|---|---|---|
| Reactivity | Moderate | High | Low |
| Thermal Stability | Excellent (up to 200°C) | Good | Fair |
| Pharma Compatibility | FDA-compliant grades available | Limited | Requires purification |
4. Customer Success Stories
Case 1: Pharmaceutical Innovator (Switzerland)
Challenge: Develop COX-2 inhibitor with improved bioavailability
Solution: Used as key intermediate in novel prodrug design
Result: 40% increase in metabolic stability vs. previous formulation
Case 2: Agrochemical Leader (Germany)
Challenge: Create broad-spectrum fungicide with lower toxicity
Solution: Incorporated into molecular backbone of new compound
Result: Achieved EC50 of 0.8 μM against Botrytis cinerea
5. Procurement Guidance
Technical Specifications Checklist
- Verify HPLC purity certificates
- Request residual solvent analysis
- Confirm particle size distribution (PSD)
Supplier Evaluation Criteria
| Factor | Importance |
|---|---|
| GMP Compliance | Critical for pharma applications |
| Batch Consistency | High (RSD <2%) |
| Packaging Options | Nitrogen-purged containers recommended |
Contact Our Experts
For technical specifications sheets or custom synthesis inquiries:
Email: info@vivalr.com
Phone: (86) 15866781826
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