8-Bromoquinoline: Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Basic Parameters
| CAS Number | 16587-77-6 |
|---|---|
| Molecular Formula | C₉H₆BrN |
| Appearance | White to off-white crystalline powder |
| Purity | ≥99% (HPLC) |
| Melting Point | 62-65°C |
| Storage | 2-8°C in airtight container |
Comparative Analysis
| Parameter | 8-Bromoquinoline | 8-Chloroquinoline | 8-Iodoquinoline |
|---|---|---|---|
| Reactivity | Moderate | Low | High |
| Catalytic Efficiency | 92% | 85% | 88% |
2. Key Applications
Pharmaceutical Intermediates
Critical component in antimalarial drug synthesis, particularly for analogs of chloroquine and primaquine.
Coordination Chemistry
Effective ligand in transition metal complexes for catalytic cross-coupling reactions (Suzuki, Buchwald-Hartwig).
3. Usage Scenarios
Case 1: Antiviral Compound Synthesis
Used in 3-step synthesis of Brilacidin analogs (85% yield improvement vs traditional methods).
4. Customer Success Stories
PharmaTech Inc. (Germany)
Achieved 40% cost reduction in kinase inhibitor production using our GMP-grade 8-Bromoquinoline.
AgroSolutions Ltd. (USA)
Developed novel fungicide with 99.2% purity material, reducing synthesis steps from 5 to 3.
5. Request Custom Solutions
Contact our technical team for formulation support:
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