Product Overview: 4-(4-Aminophenyl)morpholin-3-one (CAS: 438056-69-0)
Table of Contents
- Technical Specifications & Comparative Analysis
- Industrial Applications & Functional Insights
- Client Success Stories
- Operational Safety & Handling Protocols
- Request Customized Solutions
Technical Specifications & Comparative Analysis
| Parameter | 4-(4-Aminophenyl)morpholin-3-one | Alternative Anticoagulant Intermediates |
|---|---|---|
| CAS Number | 438056-69-0 | 1252018-10-2 (Rivaroxaban Intermediate 3) |
| Molecular Formula | C10H12N2O2 | C21H20ClN3O4 |
| Molecular Weight | 192.21 g/mol | 414.85 g/mol |
| Purity Grade | HPLC ≥98% | HPLC ≥97% |
| Thermal Stability | Stable below 25°C | Stable below 30°C |
Industrial Applications & Functional Insights
This high-purity intermediate enables:
- Synthesis of Rivaroxaban API batches meeting EP/USP standards
- Production of novel Factor Xa inhibitors under cGMP conditions
- Development of sustained-release anticoagulant formulations
Client Success Stories
Case 1: Pharmaceutical Innovator – Shanghai Jining Bioresearch
Challenge: Required 99.5% pure intermediate for NDA submission
Solution: Custom synthesis with process analytical technology (PAT)
Outcome: Accelerated FDA approval timeline by 4 months
Case 2: Contract Manufacturer – Wuhan Xinxin Jiali Biotech
Challenge: Scaling from lab to 500kg/month production
Solution: Optimized catalytic hydrogenation process
Result: 22% yield improvement with 99.3% consistency
Operational Safety & Handling Protocols
| Risk Factor | Control Measures |
|---|---|
| Skin Contact | Wear nitrile gloves (0.11mm minimum) |
| Eye Exposure | ANSI Z87.1-compliant goggles required |
| Inhalation Risk | Local exhaust ventilation (LEV) with HEPA filtration |
Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ orders)
- Regulatory support documentation
- Custom synthesis projects
Email: info@vivalr.com
Phone: (86) 15866781826
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