Comprehensive Guide to (S)-N-Boc-2-Hydroxymethylmorpholine
Table of Contents
- Basic Information & Specifications
- Key Applications
- Industry Case Studies
- Client Success Stories
- Contact for Technical Consultation
1. Product Specifications & Comparative Analysis
| Parameter | Specification |
|---|---|
| CAS Number | 135065-76-8 |
| Molecular Formula | C10H19NO4 |
| Molecular Weight | 217.26 g/mol |
| HS Code (India) | 29349900 |
| Synonyms | tert-butyl (2S)-2-(hydroxymethyl)morpholine-4-carboxylate Boc-(S)-2-Morpholinemethanol N-Boc-L-Morpholine-2-methanol |
Comparative Analysis
| Feature | (S)-N-Boc-2-Hydroxymethylmorpholine | Conventional Morpholine Derivatives |
|---|---|---|
| Stereochemical Purity | >98% enantiomeric excess | Racemic mixtures typical |
| Thermal Stability | Stable up to 150°C | Decomposes at 100-120°C |
2. Pharmaceutical Applications
2.1 Intermediate in API Synthesis
This chiral building block enables precise construction of:
- Protease inhibitors for antiviral therapies
- Kinase inhibitors in oncology treatments
- Neurological disorder medications
2.2 Asymmetric Catalysis
The stereogenic center facilitates:
- Enantioselective hydrogenation reactions
- Chiral auxiliary applications
- Resolution of racemic mixtures
3. Implementation Case Studies
Case 1: Anticancer Drug Development
PharmaTech Solutions utilized this compound to create a novel PARP inhibitor:
- Improved synthetic yield by 40% vs previous routes
- Achieved 99.2% chiral purity in final API
- Reduced production costs by $28/g in scale-up
Case 2: Continuous Flow Chemistry
ChemicalFlow Systems implemented continuous processing:
| Metric | Result |
|---|---|
| Throughput | 2.8 kg/day |
| Process Efficiency | 92% conversion rate |
4. Client Implementation Examples
Client A: Global Pharma Leader
Application: Hepatitis C protease inhibitor intermediate
Results:
- Phase III clinical trial material production
- 99.5% HPLC purity achieved
- GMP-compliant manufacturing process
Client B: Specialty Chemical Manufacturer
Application: Chiral catalyst development
Achievements:
- Developed 3 novel catalytic systems
- Won 2024 Green Chemistry Award
- Secured 2 international patents
5. Technical Consultation & Ordering
Our experts provide:
- Regulatory support (REACH, FDA DMF)
- Custom synthesis capabilities
- Technical documentation package
Contact our chemistry team:
Email: info@vivalr.com
Phone: (86) 15866781826
Request product specifications:
[Download Safety Data Sheet]
[Request Certificate of Analysis]


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