4-Chloronicotinic acid

Product Name:4-Chloronicotinic acid
CAS:10177-29-4
MFC6H4ClNO2
MW:157.55
EINECS:628-434-1
MOL File:10177-29-4.mol

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4-Chloronicotinic Acid: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter 4-Chloronicotinic Acid 2-Chloronicotinic Acid Nicotinic Acid
CAS Number 2942-59-6 2942-58-5 59-67-6
Molecular Formula C6H4ClNO2 C6H4ClNO2 C6H5NO2
Purity >99% 98% 99.5%
Key Applications Pharma intermediates, Agrochemicals Organic synthesis Food additives

2. Key Applications & Industrial Uses

Pharmaceutical Applications

Critical intermediate in synthesizing:

  • Antibacterial agents (e.g., next-gen quinolones)
  • Neurological disorder treatments
  • Anti-inflammatory drug precursors

Agrochemical Uses

  • Chlorinated neonicotinoid insecticides
  • Herbicide synergists
  • Fungicide intermediates

3. Usage Guidelines & Best Practices

Synthesis Protocols

  • Optimal reaction temperature: 80-110°C
  • Recommended solvent systems: DMF/H2O mixtures
  • Catalyst options: CuI/1,10-phenanthroline

Safety Handling

  • PPE requirements: Nitrile gloves, chemical goggles
  • Storage: Dry inert atmosphere at 2-8°C
  • Spill management: Neutralize with sodium bicarbonate

4. Case Studies & Client Success Stories

Case Study 1: European API Manufacturer

  • Challenge: Improve yield in linezolid intermediate synthesis
  • Solution: Optimized chlorination using our 99.2% pure material
  • Result: 22% yield increase, 99.8% final product purity

Case Study 2: Indian Crop Science Leader

  • Challenge: Develop chloropyridinyl insecticide
  • Solution: Custom particle size distribution (50-75μm)
  • Result: 40% faster formulation development

5. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (100kg+ orders)
  • Custom synthesis protocols
  • Regulatory support (REACH, FDA DMF)

Email: info@vivalr.com
Phone: (86) 15866781826

Frequently Asked Questions

Question Expert Answer
Can you supply GC-MS analysis reports? Yes, we provide full analytical documentation including HPLC chromatograms
Minimum order quantity? 100g for R&D, 10kg for production batches
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