4-Cloromethyl-5-methyl-1,3-dioxol-2-one (CAS 80841-78-7) Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 4-Cloromethyl-5-methyl-1,3-dioxol-2-one |
| CAS Number | 80841-78-7 |
| Molecular Formula | C5H5ClO3 |
| Appearance | Pale yellow liquid |
| Purity | ≥98% (Pharmaceutical grade) |
| Density | 1.36 g/cm³ |
| Boiling Point | 93°C at 2 mmHg |
| Flash Point | 129°C |
| Storage | 2-8°C refrigeration |
2. Key Applications
Pharmaceutical Intermediate
- Critical component in antihypertensive drug Olmesartan Medoxomil synthesis
- Intermediate for antibiotic Lenampicillin Hydrochloride production
Chemical Synthesis
- Enables selective functional group transformations under mild conditions
- Used in polymer chemistry for controlled molecular weight development
3. Usage Scenarios
Optimal Reaction Conditions
| Parameter | Optimal Range |
|---|---|
| Temperature | 25-35°C |
| Catalyst | ZnCl2 (0.67:1 mass ratio) |
| Reaction Time | 4-6 hours |
Handling Precautions
- Maintain nitrogen atmosphere for moisture-sensitive reactions
- Use anhydrous solvents for best results
4. Client Success Stories
Case 1: Leading Antihypertensive Producer
- Client: Top 10 Global Pharma Company
- Application: Olmesartan API production
- Results: 22% yield improvement vs traditional methods
- Purity Achieved: 99.7% (HPLC)
Case 2: Specialty Chemical Manufacturer
- Client: EU-Based Fine Chemicals Supplier
- Application: High-purity intermediates for radiopharmaceuticals
- Results: 40% reduction in purification steps
- Annual Usage: 850 kg
5. Technical Inquiry
Request custom synthesis plans or bulk pricing:
| Technical Support | info@vivalr.com |
| Sales Team | (86) 15866781826 |
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