D-Tetrandrine CAS 518-34-3

D-Tetrandrine (CAS 518-34-3) Product Guide

Contents

• Product Specifications & Comparative Analysis
• Applications & Functional Mechanisms
• Operational Protocols & Safety Guidelines
• Industry Applications & Case Studies
• Client Success Stories
• Expert Consultation & Procurement Support

1. Product Specifications & Comparative Analysis

2. Applications & Functional Mechanisms

Primary Applications:

• Anti-tumor research (NF-κB pathway inhibition)
• Anti-inflammatory agent (COX-2 suppression)
• Calcium channel blockade studies
• Multidrug resistance reversal in chemotherapy

Emerging Uses:

• Antiviral candidate research (HIV-1)
• Fibrosis treatment development
• Immune response modulation

3. Operational Protocols & Safety Guidelines

Experimental Handling:

1. Reconstitute in DMSO at 10 mM stock concentration
2. Working concentrations: 1-50 μM (cell culture)
3. Protect from light exposure

Safety Parameters:

• LD₅₀ (oral): 320 mg/kg (rat model)
• PPE Requirements: Gloves, lab coat, eye protection

4. Industry Applications & Case Studies

Pharmaceutical Development:

• Phase II clinical trial adjuvant (NSCLC treatment)
• Synergistic use with paclitaxel (ovarian cancer)

Academic Research:

• Autophagy mechanism studies (Shanghai Jiao Tong University)
• Cardiotoxicity mitigation research (Mayo Clinic)

5. Client Success Stories

Case 1: Oncology Research Center

• Application: Triple-negative breast cancer models
• Result: 62% tumor growth inhibition at 25 μM
• Client Feedback: “Consistent batch quality enabled reproducible results”

Case 2: Biotech Startup

• Application: Pulmonary fibrosis drug discovery
• Result: 40% reduction in collagen deposition (murine model)
• Client Feedback: “Technical support accelerated our screening process”

6. Expert Consultation & Procurement Support

Contact our alkaloid specialists for:

• Bulk order pricing (GMP-grade available)
• Custom formulation services
• Regulatory documentation support

Email: info@vivalr.com
Phone: (86) 15866781826

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