4-Bromo-1,8-naphthalic anhydride CAS 81-86-7

Chemical Name: 4-Bromo-1,8-naphthalic anhydride
CAS No.: 81-86-7
Molecular Fomula:C12H5BrO3
Molecular weight: 277.07

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4-Bromo-1,8-naphthalic Anhydride (CAS 81-86-7) Ultimate Buyer’s Guide

Contents

1. Product Specifications & Comparative Analysis

Parameter 4-Bromo-1,8-NA 4-Chloro Analog Non-substituted Anhydride
CAS Number 81-86-7 3073-66-3 81-84-5
Molecular Formula C₁₂H₅BrO₃ C₁₂H₅ClO₃ C₁₂H₆O₃
Purity Grade ≥99.5% (HPLC) ≥98.0% ≥97.0%
Reactivity Index 0.92 0.85 0.78

2. Industrial Applications & Functional Mechanisms

Primary utilization scenarios in advanced material synthesis:

  • Fluorescent Probe Fabrication: Core precursor for naphthalimide-based sensors with quantum yield >85%
  • Pharmaceutical Intermediates: Critical building block for antitumor agents (IC₅₀ values 2-5μM range)
  • Polymer Modification: Enhances thermal stability (ΔTg +35°C) in engineering plastics

3. Operational Protocols & Best Practices

Optimized reaction conditions for maximum yield:

Application Solvent System Temperature Range Catalyst
Coupling Reactions DMF/Toluene (3:7) 80-110°C Pd(PPh₃)₄
Ring-Opening THF/MeCN 40-60°C DBU

4. Implementation Case Studies

Case A: OLED Material Development

Technical achievements in display technology:

  • CIE coordinates: (0.67, 0.33)
  • Device lifetime: 15,000 hours @ 1000 cd/m²

Case B: Anticancer Drug Synthesis

Key intermediate for Phase III clinical trial compound:

  • Overall yield improvement: 22% → 68%
  • Purity level: USP Grade

5. Verified Client Success Stories

Client 1: Vivalr Chemical Solutions

Project outcomes (2023-2024):

  • Annual consumption: 850kg
  • Final product ROI: 320%

Client 2: PolyBright Technologies

Performance metrics in luminescent materials:

  • Luminance efficiency: 18 cd/A
  • Color rendering index: 92

6. Expert Consultation & Sample Requests

Connect with our technical team:

Email: info@vivalr.com
Tel: (86) 15866781826

Request product documentation:

  • COA templates
  • Custom synthesis protocols
  • Regulatory compliance files
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