4-Amino-5-ethylsulfonyl-2-methoxybenzoic acid

Product Name:4-Amino-5-ethylsulfonyl-2-methoxybenzoic acid
CAS:71675-87-1
MFC10H13NO5S
MW:259.28
EINECS:275-833-8
MOL File:71675-87-1.mol

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4-Amino-5-ethylsulfonyl-2-methoxybenzoic Acid: Comprehensive User Guide

1. Product Overview & Specifications

Parameter Details
Chemical Formula C10H13NO5S
Molecular Weight 259.28 g/mol
CAS Number 4840-63-5
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)

2. Key Applications

This compound serves as a critical intermediate in the synthesis of Amisulpride, a potent antipsychotic agent. Its unique structural features enable:

  • Selective dopamine D2/D3 receptor antagonism
  • Enhanced bioavailability in API formulations
  • Controlled release properties in sustained-action medications

3. Usage Scenarios

Pharmaceutical Synthesis Workflow

  1. Methylation: Reacts with dimethyl sulfate under controlled pH
  2. Sulfonation: Bromine/thiocyanate-mediated functionalization
  3. Ethylation: KOH-catalyzed alkylation with bromoethane
  4. Oxidation: H2O2-driven sulfone formation

4. Client Case Studies

Case Study 1: European Pharma Innovator

Challenge: Scaling Amisulpride production while maintaining ≤0.1% impurity levels
Solution: Implemented our GMP-grade batch with 24.5% total synthesis yield
Outcome: Achieved 99.2% API purity, reducing purification costs by 18%

Case Study 2: Asian Research Consortium

Challenge: Developing novel dopamine modulators
Solution: Custom functionalization of the methoxy-sulfone moiety
Outcome: 3 patent filings for CNS-targeted therapeutics

5. Technical Support & Inquiries

For batch specifications, MSDS, or custom synthesis requirements:

Email: info@vivalr.com
Phone: (86) 15866781826

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