Methyl Quinoline-6-Carboxylate: Comprehensive Technical Guide
Table of Contents
1. Key Parameters & Comparative Analysis
| Parameter | Methyl Quinoline-6-Carboxylate | Methyl 2-Methylquinoline-6-Carboxylate | Methyl 4-Chloroquinoline-6-Carboxylate |
|---|---|---|---|
| CAS Number | 38896-30-9 | 108166-01-4 | 648449-01-8 |
| Molecular Formula | C11H9NO2 | C12H11NO2 | C11H8ClNO2 |
| Molecular Weight | 187.195 g/mol | 201.22 g/mol | 221.64 g/mol |
| Melting Point | 88°C | N/A | N/A |
| Boiling Point | 315.1±15.0°C | N/A | N/A |
| Density | 1.2±0.1 g/cm³ | N/A | N/A |
2. Functional Applications
Methyl quinoline-6-carboxylate and its derivatives serve as critical intermediates in pharmaceutical synthesis and organic chemistry research. Key applications include:
- Drug Development: Precursor for synthesizing antimicrobial, antimalarial, and anticancer agents due to the quinoline scaffold’s bioactivity.
- Chemical Research: Building block for heterocyclic compounds in academic and industrial R&D.
- Material Science: Used in advanced material synthesis for optoelectronic applications.
3. Practical Use Cases
- Antibacterial Agent Synthesis: Functionalized to create novel quinolone antibiotics targeting resistant pathogens.
- Catalyst Design: Modified with halogen or methyl groups to enhance catalytic efficiency in cross-coupling reactions.
- Fluorescent Probe Development: Incorporated into probes for detecting metal ions in biological systems.
4. Client Success Stories
Case 1: Pharmaceutical Intermediate Supply
Client: A Shanghai-based biotech firm specializing in antiviral drug development.
Application: Supplied methyl quinoline-6-carboxylate for synthesizing a preclinical candidate targeting RNA viruses. Achieved 98% purity, accelerating lead optimization.
Case 2: Custom Derivative Synthesis
Client: A European research institute studying kinase inhibitors.
Solution: Delivered 4-chloro and 2-methyl derivatives with >99% HPLC purity, enabling structure-activity relationship studies.
5. Inquiry & Custom Solutions
For technical specifications, bulk pricing, or custom synthesis services:
Email: info@vivalr.com
Tel: (86) 15866781826


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