5,6-Dichloronicotinic acid

Product Name:5
6-Dichloronicotinic acid
CAS:41667-95-2
MFC6H3Cl2NO2
MW:192
EINECS:609-951-1
MOL File:41667-95-2.mol

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Table of Contents

1. Product Overview

5,6-Dichloronicotinic Acid (CAS 33252-28-7)

Parameter Description
Chemical Formula C6H3Cl2NO2
Molecular Weight 192.00 g/mol
Appearance White to off-white crystalline powder
Purity ≥98% (HPLC)
Melting Point 168-172°C
Solubility Soluble in DMSO, methanol; slightly soluble in water

2. Specifications & Comparative Analysis

Feature 5,6-Dichloronicotinic Acid 2-Chloronicotinic Acid 3,5-Dichloropicolinic Acid
Chlorine Positions 5,6-positions 2-position 3,5-positions
Pharmaceutical Use High Moderate Low
Agrochemical Efficiency Superior herbicidal activity Moderate Specialized applications
Price per kg $850-$1,200 $600-$900 $1,100-$1,500

3. Key Applications

3.1 Pharmaceutical Intermediate

Critical precursor for:

  • Antibiotic derivatives
  • Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Kinase inhibitor synthesis

3.2 Agrochemical Formulations

  • Broad-spectrum herbicide active ingredient
  • Plant growth regulator compositions

3.3 Organic Synthesis

  • Ligand in coordination chemistry
  • Building block for metal-organic frameworks (MOFs)

4. Industry Case Studies

4.1 PharmaCorp – Antibiotic Synthesis

Challenge: Required high-purity intermediate for next-gen quinolone antibiotics
Solution: Custom synthesis of 99.2% pure 5,6-Dichloronicotinic Acid
Outcome: 23% yield improvement vs traditional chlorination methods

4.2 AgroGrowth Ltd. – Herbicide Development

Challenge: Needed persistent weed control in rice paddies
Solution: Formulated 40% SC containing 5,6-Dichloronicotinic Acid
Result: 98% efficacy against Echinochloa crus-galli

4.3 ChemSynth Research – Catalysis Development

Objective: Create novel palladium complex catalyst
Process: Used as chelating ligand in cross-coupling reactions
Achievement: Achieved 92% yield in Suzuki-Miyaura reactions

5. Usage Guidelines

Aspect Specification
Storage 2-8°C in airtight container
Handling Use NIOSH-certified respirator when handling powder
Incompatibilities Strong oxidizers, alkaline metals
Shelf Life 24 months when stored properly

6. Request Quotation

Contact our chemical specialists for:

  • Bulk pricing (100kg+ orders)
  • Custom synthesis requirements
  • Technical support

Email: info@vivalr.com
Phone: (86) 15866781826

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