2-Bromoquinoline: Comprehensive Guide for Researchers & Industry Professionals
Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Performance Comparison: 2-Bromoquinoline vs Alternatives
- 4. Operational Guidelines & Best Practices
- 5. Verified Case Studies
- 6. Inquiry & Technical Support
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | 2-Bromoquinoline |
| CAS Number | 5332-25-2 |
| Molecular Formula | C9H6BrN |
| Purity | ≥98% (HPLC) |
| Appearance | White to pale yellow crystalline powder |
| Melting Point | 84-86°C |
| Storage | 2-8°C in airtight container |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate: Critical precursor for kinase inhibitors (e.g., ALK5 inhibitors) and antiviral agents.
Agrochemical Synthesis: Building block for fungicides and herbicides with enhanced bioactivity.
Material Science: Ligand in transition metal catalysts for cross-coupling reactions.
3. Performance Comparison
| Property | 2-Bromoquinoline | 2-Chloroquinoline | 2-Iodoquinoline |
|---|---|---|---|
| Reactivity | High | Moderate | Very High |
| Stability | Excellent | Good | Poor |
| Price Competitiveness | $$ | $ | $$$ |
| Catalytic Efficiency | 92% | 85% | 94% |
4. Operational Guidelines
Lab-Scale Handling:
- Use dry DMF as solvent for Buchwald-Hartwig aminations
- Optimal catalyst loading: 2 mol% Pd(dba)2
Industrial Protocols:
- Maintain nitrogen atmosphere during large-scale coupling reactions
- Recommended reaction temperature: 80-110°C
5. Verified Case Studies
Case 1: Antiviral Drug Development
Client: Shanghai PharmaTech Co., Ltd. (GMP-certified facility)
Application: Synthesis of broad-spectrum antiviral compound
Result: Achieved 78% yield improvement vs previous chlorinated analog
Case 2: OLED Material Production
Client: Korea Advanced Materials Institute
Application: Electron-transport layer precursor
Result: Enhanced device lifetime by 40% with 99.2% purity batch
6. Inquiry & Technical Support
Contact our chemistry experts for:
- Custom synthesis requirements
- Bulk pricing (50kg+ quantities available)
- Technical documentation (COA, MSDS, stability data)
Email: info@vivalr.com
Phone: (86) 15866781826


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