2-Bromopyridine-5-carbaldehyde: Comprehensive Industry Guide
Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Practical Usage Scenarios
- 4. Client Success Stories
- 5. Frequently Asked Questions (FAQ)
- 6. Request Customized Solutions
1. Product Overview & Specifications
| Parameter | 2-Bromopyridine-5-carbaldehyde | Comparable Compound |
|---|---|---|
| CAS Number | 102003-73-6 | 2-Chloropyridine-5-carbaldehyde (874-86-6) |
| Molecular Formula | C6H4BrNO | C6H4ClNO |
| Purity | ≥98% (HPLC) | ≥95% |
| Key Advantage | Superior leaving group for nucleophilic substitution | Lower reactivity in coupling reactions |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
Critical precursor for:
- Kinase inhibitor development (e.g., EGFR inhibitors)
- Antiviral drug candidates targeting RNA viruses
Agrochemical Synthesis
Used in novel pesticide development:
- Neonicotinoid alternatives
- Fungicidal pyridine derivatives
3. Practical Usage Scenarios
Suzuki-Miyaura Cross-Coupling
Typical reaction conditions:
| Component | Specification |
|---|---|
| Catalyst | Pd(PPh3)4 (5 mol%) |
| Base | K2CO3 (2 equiv) |
| Yield | 82-89% (reported) |
4. Client Success Stories
Case 1: Top 10 Pharma Company
Challenge: Required high-purity intermediate for Phase III oncology drug
Solution: Custom synthesis at 99.5% purity with strict residual solvent control
Outcome: Accelerated IND submission by 8 weeks
Case 2: Electronic Materials Developer
Challenge: Needed brominated precursor for OLED transport layer
Solution: Bulk supply with ≤50 ppm metal impurities
Outcome: Achieved 18% improvement in device efficiency
5. Frequently Asked Questions
Q: What’s the recommended storage condition?
A: Store at 2-8°C under inert gas (N2 or Ar) in amber glass containers.
Q: Can you supply under TSCA compliance?
A: Yes, all shipments include full regulatory documentation packages.
6. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100kg+ quantities available)
- Custom purity profiles (up to 99.99%)
- GMP-grade synthesis options
Email: info@vivalr.com
Phone: (86) 15866781826


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