2-Bromopyridine-5-carbaldehyde

Product Name:2-Bromopyridine-5-carbaldehyde
CAS:149806-06-4
MFC6H4BrNO
MW:186.01
EINECS:629-088-4
MOL File:149806-06-4.mol

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2-Bromopyridine-5-carbaldehyde: Comprehensive Industry Guide

Contents

1. Product Overview & Specifications

Parameter 2-Bromopyridine-5-carbaldehyde Comparable Compound
CAS Number 102003-73-6 2-Chloropyridine-5-carbaldehyde (874-86-6)
Molecular Formula C6H4BrNO C6H4ClNO
Purity ≥98% (HPLC) ≥95%
Key Advantage Superior leaving group for nucleophilic substitution Lower reactivity in coupling reactions

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Critical precursor for:

  • Kinase inhibitor development (e.g., EGFR inhibitors)
  • Antiviral drug candidates targeting RNA viruses

Agrochemical Synthesis

Used in novel pesticide development:

  • Neonicotinoid alternatives
  • Fungicidal pyridine derivatives

3. Practical Usage Scenarios

Suzuki-Miyaura Cross-Coupling

Typical reaction conditions:

Component Specification
Catalyst Pd(PPh3)4 (5 mol%)
Base K2CO3 (2 equiv)
Yield 82-89% (reported)

4. Client Success Stories

Case 1: Top 10 Pharma Company

Challenge: Required high-purity intermediate for Phase III oncology drug
Solution: Custom synthesis at 99.5% purity with strict residual solvent control
Outcome: Accelerated IND submission by 8 weeks

Case 2: Electronic Materials Developer

Challenge: Needed brominated precursor for OLED transport layer
Solution: Bulk supply with ≤50 ppm metal impurities
Outcome: Achieved 18% improvement in device efficiency

5. Frequently Asked Questions

Q: What’s the recommended storage condition?

A: Store at 2-8°C under inert gas (N2 or Ar) in amber glass containers.

Q: Can you supply under TSCA compliance?

A: Yes, all shipments include full regulatory documentation packages.

6. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (100kg+ quantities available)
  • Custom purity profiles (up to 99.99%)
  • GMP-grade synthesis options

Email: info@vivalr.com
Phone: (86) 15866781826

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