2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene: Technical Guide & Application Insights
Table of Contents
1. Product Overview & Specifications
| Parameter | Value |
|---|---|
| Chemical Name | 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene |
| CAS Number | 898566-17-1 |
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.2716 g/mol |
| Structural Features | Fluorophenyl group, iodinated methylphenyl substituent, thiophene backbone |
2. Key Applications
This organoiodine compound serves as:
- Intermediate in pharmaceutical synthesis (e.g., kinase inhibitors)
- Building block for functional materials in OLED research
- Probe molecule in fluorine-19 NMR studies
- Precursor for cross-coupling reactions in catalysis
3. Usage Scenarios
3.1 Medicinal Chemistry
Used in lead optimization for targeted cancer therapies due to its dual halogen substitution enabling selective protein interactions.
3.2 Material Science
Employed in developing charge-transport layers where the thiophene core enhances electron mobility (typical μe > 10-3 cm²/V·s).
4. Client Case Studies
Case 1: Pharmaceutical Developer (Confidential)
Challenge: Required stable iodine-containing intermediate for PET tracer development
Solution: Supplied 98.7% pure compound with validated stability data (-20°C storage, 24-month shelf life)
Outcome: Accelerated preclinical testing timeline by 40%
Case 2: University Research Team
Project: Synthesis of donor-acceptor polymers
Result: Achieved 12.3% PCE in organic photovoltaic devices using our compound as electron donor
5. Contact for Custom Solutions
Request technical documents (COA, MSDS) or discuss bulk orders:
| info@vivalr.com | |
| Phone | (86) 15866781826 |
| Lead Time | 4-6 weeks for GMP-grade batches |


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