Comprehensive Guide to (R)-3-(Boc-Amino)piperidine: Applications, Case Studies & Technical Specifications
Table of Contents
1. Product Overview & Specifications
| Parameter | (R)-3-(Boc-Amino)piperidine | Competitor Product A | Competitor Product B |
|---|---|---|---|
| CAS Number | 135081-05-7 | 135081-04-6 | 135081-03-5 |
| Purity | ≥99% (HPLC) | ≥97% | ≥95% |
| Storage Temp | -20°C | 2-8°C | Room Temp |
| Boc Stability | 24 months | 12 months | 6 months |
Key Advantages: Superior stereochemical purity (99% ee), extended shelf life, and optimized solubility in common organic solvents.
2. Key Applications & Use Cases
2.1 Pharmaceutical Intermediate
Widely used in synthesis of:
- Kinase inhibitors (EGFR, ALK)
- Antidepressant APIs
- Antiviral prodrugs
2.2 Peptide Modification
Enables precise N-terminal modifications in:
- GPCR-targeted therapeutics
- Cell-penetrating peptides
3. Operational Guidelines
3.1 Handling Protocol
- Storage: Maintain inert atmosphere (Ar/N2)
- Reactivation: Pre-warm to 25°C before use
3.2 Boc Deprotection
Recommended conditions:
- TFA/DCM (1:4 v/v), 0-5°C, 2hr
- HCl/dioxane (4M), RT, 4hr
4. Industry Case Studies
Case 1: Oncology Drug Development
Client: Top 10 Pharma Company (Confidential)
- Application: Third-generation EGFR inhibitor synthesis
- Result: Improved yield by 22% vs. previous intermediates
Case 2: CNS Drug Optimization
Client: NeuroThera Solutions
- Application: Serotonin receptor modulator development
- Result: Achieved 99.3% chiral purity in final API
5. Technical Support & Inquiry
Contact our chemists for custom synthesis requests or technical guidance:
| info@vivalr.com | |
| Phone | +86 15866781826 |
| Lead Time | 2-3 weeks for bulk orders (>5kg) |
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