(S)-1-Boc-3-hydroxypiperidine

Product Name:(S)-1-Boc-3-hydroxypiperidine
CAS:143900-44-1
MFC10H19NO3
MW:201.26
EINECS:1308068-626-2
MOL File:143900-44-1.mol

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Table of Contents

(S)-1-Boc-3-hydroxypiperidine: Product Overview & Specifications

Chemical Profile

Parameter Specification
CAS Number 143900-44-1
Molecular Formula C10H19NO3
Molecular Weight 201.27 g/mol
Appearance White crystalline powder
Purity (HPLC) >98%
Storage 2-8°C in dry environment

Comparative Analysis

Feature (S)-1-Boc-3-hydroxypiperidine Similar Compounds
Boc Protection Acid-labile group Cbz (base-sensitive)
Chirality Single enantiomer Racemic mixtures
Solubility Soluble in DCM, THF Limited in polar solvents

Key Applications in Pharmaceutical Chemistry

Drug Intermediate Applications

Widely used as chiral building block in:

  • Protease inhibitor development (HIV/AIDS therapeutics)
  • Kinase-targeted cancer treatments
  • Neurological disorder drug candidates

Synthetic Chemistry Uses

  • Asymmetric synthesis catalyst
  • Peptidomimetic scaffold construction
  • Protecting group strategies

Usage Guidelines & Safety Protocol

Handling Recommendations

  • Use nitrile gloves and safety goggles
  • Operate under fume hood
  • Avoid contact with strong acids/bases

Storage Conditions

  • Sealed amber glass containers
  • Desiccated environment
  • Limited exposure to oxygen

Industry Case Studies

Case Study 1: Antiviral Drug Development

Client Top 10 Global Pharma Company
Application HIV-1 protease inhibitor intermediate
Result 20% yield improvement vs previous synthon
Client Feedback “Critical for chiral purity requirements”

Case Study 2: Oncology Research

Client Biotech Startup (NASDAQ-listed)
Application BTK inhibitor scaffold modification
Result Accelerated lead optimization by 6 months
Client Feedback “Reliable supply enabled IND filing”

Technical & Purchasing Support

Contact Our Experts

For batch-specific COA, bulk pricing, or custom synthesis:

Why Choose Us?

  • GMP-grade production facilities
  • Strict QC: HPLC, NMR, MS testing
  • Global logistics network
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