3-Quinolineboronic Acid User Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Applications & Industry Use Cases
- 3. Operational Guidelines & Safety Protocols
- 4. Client Success Stories
- 5. Request Customized Quotation
1. Product Specifications & Comparative Analysis
| Parameter | 3-Quinolineboronic Acid | 2-Quinolineboronic Acid | 4-Pyridineboronic Acid |
|---|---|---|---|
| CAS Number | 1072948-13-6 | N/A | N/A |
| Molecular Formula | C₉H₈BNO₂ | C₉H₈BNO₂ | C₅H₆BNO₂ |
| Purity | >97% (HPLC) | >95% | >98% |
| Key Advantage | Superior Suzuki coupling efficiency | Limited solubility | Lower thermal stability |
2. Applications & Industry Use Cases
Pharmaceutical Intermediates
Critical for synthesizing kinase inhibitors (e.g., EGFR, ALK) in oncology research.
Material Science
Used in OLED precursor development for enhanced electron transport layers.
Agrochemicals
Key component in novel pesticide formulations with improved environmental profiles.
3. Operational Guidelines & Safety Protocols
Storage Requirements
Store at 2-8°C under inert gas (Ar/N₂) with desiccant. Shelf life: 24 months unopened.
Reaction Optimization
Recommended conditions for Suzuki coupling: 1.2 eq boronic acid, Pd(PPh₃)₄ catalyst (2 mol%), K₂CO₃ base in THF/H₂O (4:1) at 80°C.
4. Client Success Stories
Case 1: Oncology Research Institute (2023)
Developed novel PARP inhibitor using 3-Quinolineboronic acid as key intermediate, achieving 92% yield in final coupling step.
Case 2: OLED Manufacturer (2024)
Integrated compound into blue-emissive layer, achieving CIE coordinates (0.15, 0.06) with 18% EQE improvement.
Case 3: Agrochemical Leader (2024)
Created systemic fungicide with 3-Quinolineboronic acid scaffold, demonstrating 99% efficacy against Puccinia striiformis.
5. Request Customized Quotation
Optimize your synthesis with batch-specific COA and technical support:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Request bulk pricing (100g-1kg batches) or inquire about custom derivatives.
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