R-3-Piperidinamine Dihydrochloride: Technical Guide & Application Solutions
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | R-3-Piperidinamine Dihydrochloride | Standard Piperidine Derivatives |
|---|---|---|
| Purity | ≥99.5% | 98.0-99.0% |
| Solubility | Water & Organic Solvents | Limited Organic Solubility |
| Storage Stability | 24 Months | 12-18 Months |
2. Pharmaceutical Applications
2.1 API Synthesis
Critical intermediate for antidepressants and Parkinson’s medications with enhanced stereochemical control.
2.2 Chiral Building Block
Enables production of enantiomerically pure compounds for CNS therapies through optimized synthetic pathways.
3. Operational Guidelines
3.1 Handling Protocols
Maintain nitrogen atmosphere during storage to prevent degradation. Use amber glass containers at 2-8°C.
3.2 Reaction Optimization
Recommended molar ratio 1:1.2 with carbonyl compounds in THF solvent at -20°C to 25°C reaction temperature.
4. Industry Use Cases
4.1 Antipsychotic Drug Synthesis
Key intermediate in Aripiprazole production, achieving 92% yield in Buchwald-Hartwig cross-coupling reactions.
4.2 Antiviral Agent Development
Used in Remdesivir analog synthesis with 99.3% enantiomeric excess in final API products.
5. Client Success Stories
5.1 PharmaGen Solutions
Implemented in selective serotonin reuptake inhibitor production: 18% reduction in side reactions, 30% faster crystallization.
5.2 BioHealth Innovations
Enabled scale-up of novel dopamine agonists from lab to 500kg batch production with 99.8% HPLC purity consistency.
6. Expert Consultation
Contact our technical team for custom synthesis solutions:
Email: info@vivalr.com
Tel: (86) 15866781826
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