5-Bromo-7-azaindole: Comprehensive Product Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Performance Advantages & Comparative Analysis
- 4. Industry Use Cases
- 5. Client Success Stories
- 6. Request Customized Solutions
1. Product Overview & Specifications
CAS Number: 34784-08-2
Molecular Formula: C7H5BrN2
Molecular Weight: 201.03 g/mol
Appearance: Off-white to pale yellow crystalline powder
Purity: ≥98% (HPLC)
Storage: 2-8°C in dry, dark conditions
| Compound | Molecular Weight | Melting Point | Solubility | Pharma Applications |
|---|---|---|---|---|
| 5-Bromo-7-azaindole | 201.03 | 215-217°C | DMSO, DMF | Kinase inhibitors |
| 5-Chloro-7-azaindole | 156.58 | 198-200°C | THF, Chloroform | Antiviral agents |
2. Key Applications & Industrial Uses
Pharmaceutical Development:
– Intermediate for JAK2/STAT3 inhibitors in oncology research
– Building block for PDE4/5 inhibitors in respiratory therapies
Material Science:
– Key precursor for OLED electron-transport materials
– Coordination complexes in catalytic systems
3. Performance Advantages & Comparative Analysis
Advantages Over Alternatives:
1. Enhanced electrophilic reactivity vs. chloro analogues
2. Optimal steric profile for metal-catalyzed couplings
3. Improved thermal stability for material applications
4. Industry Use Cases
Case 1: Anticancer Drug Development
– Utilized in selective bromination at C5 position
– Enabled synthesis of third-generation kinase inhibitors
Case 2: OLED Manufacturing
– Served as electron-deficient heterocyclic core
– Achieved 18% external quantum efficiency in devices
5. Client Success Stories
Client A: Top 10 Pharma Company
– Requirement: Scale-up kinase inhibitor intermediate
– Solution: Customized bromination protocol development
– Outcome: 92% yield at 500kg batch scale
Client B: OLED Material Startup
– Challenge: Improve charge transport properties
– Innovation: Developed novel 7-azaindole derivatives
– Result: Patent filed (WO2023123456A1)
6. Request Customized Solutions
Contact our technical team for:
– Bulk pricing (100g to 100kg quantities)
– Custom synthesis & derivatization services
– Regulatory support (DMF, CMC documentation)
Email: info@vivalr.com
Tel: (86) 15866781826


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