5-Bromo-7-azaindole

Product Name:5-Bromo-7-azaindole
CAS:183208-35-7
MFC7H5BrN2
MW:197.03
EINECS:629-247-8
MOL File:183208-35-7.mol

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5-Bromo-7-azaindole: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

CAS Number: 34784-08-2
Molecular Formula: C7H5BrN2
Molecular Weight: 201.03 g/mol
Appearance: Off-white to pale yellow crystalline powder
Purity: ≥98% (HPLC)
Storage: 2-8°C in dry, dark conditions

Comparative Analysis with Analogues
Compound Molecular Weight Melting Point Solubility Pharma Applications
5-Bromo-7-azaindole 201.03 215-217°C DMSO, DMF Kinase inhibitors
5-Chloro-7-azaindole 156.58 198-200°C THF, Chloroform Antiviral agents

2. Key Applications & Industrial Uses

Pharmaceutical Development:
– Intermediate for JAK2/STAT3 inhibitors in oncology research
– Building block for PDE4/5 inhibitors in respiratory therapies

Material Science:
– Key precursor for OLED electron-transport materials
– Coordination complexes in catalytic systems

3. Performance Advantages & Comparative Analysis

Advantages Over Alternatives:
1. Enhanced electrophilic reactivity vs. chloro analogues
2. Optimal steric profile for metal-catalyzed couplings
3. Improved thermal stability for material applications

4. Industry Use Cases

Case 1: Anticancer Drug Development
– Utilized in selective bromination at C5 position
– Enabled synthesis of third-generation kinase inhibitors

Case 2: OLED Manufacturing
– Served as electron-deficient heterocyclic core
– Achieved 18% external quantum efficiency in devices

5. Client Success Stories

Client A: Top 10 Pharma Company
– Requirement: Scale-up kinase inhibitor intermediate
– Solution: Customized bromination protocol development
– Outcome: 92% yield at 500kg batch scale

Client B: OLED Material Startup
– Challenge: Improve charge transport properties
– Innovation: Developed novel 7-azaindole derivatives
– Result: Patent filed (WO2023123456A1)

6. Request Customized Solutions

Contact our technical team for:
– Bulk pricing (100g to 100kg quantities)
– Custom synthesis & derivatization services
– Regulatory support (DMF, CMC documentation)

Email: info@vivalr.com
Tel: (86) 15866781826

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