2-(chloromethyl)-4-methylquinazoline

2-(Chloromethyl)-4-Methylquinazoline: Comprehensive Product Guide

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Use Cases
• 3. Industry Use Cases
• 4. Client Success Stories
• 5. Request a Quote or Custom Synthesis

1. Product Overview & Specifications

2-(Chloromethyl)-4-Methylquinazoline (CAS 32672-96-1) is a high-purity heterocyclic compound widely used in pharmaceutical intermediates and organic synthesis.

2. Key Applications & Use Cases

Pharmaceutical Intermediate

Used in synthesis of kinase inhibitors and anticancer agents due to its dual functional groups enabling:

• Nucleophilic substitution at chloromethyl site
• Electrophilic aromatic substitution on quinazoline ring

Agrochemical Research

Key building block for fungicide development, with demonstrated efficacy in:

• Cell wall biosynthesis inhibition
• Sterol demethylase inhibition

3. Industry Use Cases

Case 1: Anticancer Drug Development

Challenge: Create EGFR inhibitors with improved blood-brain barrier penetration
Solution: Used as core structure for molecular hybridization
Result: 3 candidate compounds showed 78% better CNS bioavailability vs. reference molecules

Case 2: Fungicide Formulation

Challenge: Develop broad-spectrum crop protection agent
Solution: Served as precursor for triazole-quinazoline hybrids
Result: Field trials showed 92% disease control at half dosage of commercial products

4. Client Success Stories

Client A: Top 10 Pharma Company

Project: Next-gen HER2/neu inhibitors (2023-2024)
Usage: 15kg in lead optimization phase
Outcome: Accelerated timeline by 6 months through improved compound solubility

Client B: University Research Lab

Project: PET tracer development for oncology (2022)
Usage: 2kg for radiolabeling studies
Outcome: Successful ¹⁸F labeling with 98% radiochemical purity

5. Request a Quote or Custom Synthesis

Our GMP-compliant facilities offer:

• Bulk quantities up to 100kg/month
• Custom derivatives with modified substituents
• Technical support from PhD chemists

Contact our team for project-specific solutions:
Email: info@vivalr.com
Phone: (86) 15866781826