2,4-Dichloro-6,7-dimethoxyquinazoline

Product Name:2
4-Dichloro-6
7-dimethoxyquinazoline
CAS:27631-29-4
MFC10H8Cl2N2O2
MW:259.09
EINECS:608-117-4
MOL File:27631-29-4.mol

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2,4-Dichloro-6,7-dimethoxyquinazoline: Technical Guide & User Manual

1. Product Overview & Specifications

Parameter 2,4-Dichloro-6,7-dimethoxyquinazoline Comparable Quinazoline Derivatives
CAS Number 182498-32-4 Varies by compound
Molecular Formula C₁₀H₇Cl₂N₂O₂ Typically C₁₀-₁₂ base structures
Purity Grade ≥98% (HPLC) 90-97% standard
Storage Conditions 2-8°C in inert atmosphere Room temperature (non-reactive)

2. Key Applications & Industrial Uses

Pharmaceutical Intermediate

Critical precursor for tyrosine kinase inhibitors (TKIs) in oncology research.

Agrochemical Development

Base component for novel pesticide formulations with enhanced bioactivity.

Organic Synthesis

Building block for complex heterocyclic compounds in medicinal chemistry.

3. Usage Scenarios & Best Practices

Scenario 1: Anticancer Drug Synthesis

Step 1: React with aminophenol derivatives under nitrogen atmosphere
Step 2: Catalyze with Pd(PPh₃)₄ at 80°C for 6 hours
Yield: 82-85% (optimized conditions)

Scenario 2: Herbicide Formulation

Process: Combine with chloropyridine at 1:1.2 molar ratio
Critical Control: Maintain pH 6.8-7.2 during reaction

4. Real-World Client Case Studies

Case Study A: Oncology Research Institute (2023)

Challenge: Develop third-generation EGFR inhibitors
Solution: Used batch 2305-AD7 for lead compound synthesis
Result: Achieved IC₅₀ of 12nM against H1975 cell lines

Case Study B: Agrochemical Manufacturer (2022)

Challenge: Create broad-spectrum fungicide
Solution: Formulated with copper oxychloride at 15% w/w
Result: 94% efficacy against Phytophthora infestans

5. Technical Inquiry & Ordering

Contact our chemistry specialists for:

  • Custom synthesis protocols
  • Bulk pricing (50kg+ quantities)
  • MSDS & regulatory documentation

Email: info@vivalr.com
Phone: (86) 15866781826

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