2,4-Dichloro-6,7-dimethoxyquinazoline: Technical Guide & User Manual
Table of Contents
1. Product Overview & Specifications
| Parameter | 2,4-Dichloro-6,7-dimethoxyquinazoline | Comparable Quinazoline Derivatives |
|---|---|---|
| CAS Number | 182498-32-4 | Varies by compound |
| Molecular Formula | C₁₀H₇Cl₂N₂O₂ | Typically C₁₀-₁₂ base structures |
| Purity Grade | ≥98% (HPLC) | 90-97% standard |
| Storage Conditions | 2-8°C in inert atmosphere | Room temperature (non-reactive) |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediate
Critical precursor for tyrosine kinase inhibitors (TKIs) in oncology research.
Agrochemical Development
Base component for novel pesticide formulations with enhanced bioactivity.
Organic Synthesis
Building block for complex heterocyclic compounds in medicinal chemistry.
3. Usage Scenarios & Best Practices
Scenario 1: Anticancer Drug Synthesis
Step 1: React with aminophenol derivatives under nitrogen atmosphere
Step 2: Catalyze with Pd(PPh₃)₄ at 80°C for 6 hours
Yield: 82-85% (optimized conditions)
Scenario 2: Herbicide Formulation
Process: Combine with chloropyridine at 1:1.2 molar ratio
Critical Control: Maintain pH 6.8-7.2 during reaction
4. Real-World Client Case Studies
Case Study A: Oncology Research Institute (2023)
Challenge: Develop third-generation EGFR inhibitors
Solution: Used batch 2305-AD7 for lead compound synthesis
Result: Achieved IC₅₀ of 12nM against H1975 cell lines
Case Study B: Agrochemical Manufacturer (2022)
Challenge: Create broad-spectrum fungicide
Solution: Formulated with copper oxychloride at 15% w/w
Result: 94% efficacy against Phytophthora infestans
5. Technical Inquiry & Ordering
Contact our chemistry specialists for:
- Custom synthesis protocols
- Bulk pricing (50kg+ quantities)
- MSDS & regulatory documentation
Email: info@vivalr.com
Phone: (86) 15866781826
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