2-Fluoroisonicotinic Acid (CAS 402-65-3): Comprehensive Technical Guide
Table of Contents
1. Chemical Identification & Specifications
| Parameter | Specification |
|---|---|
| IUPAC Name | 2-Fluoro-4-pyridinecarboxylic acid |
| CAS Number | 402-65-3 |
| Molecular Formula | C6H4FNO2 |
| Molecular Weight | 141.10 g/mol |
| Structural Analogues | 2-Fluoropyridine-4-carboxylic acid 2-Fluoroisonicotinic acid 2-Fluoro-4-carboxypyridine |
2. Applications & Industrial Uses
Pharmaceutical Intermediates
This fluorinated pyridine derivative serves as critical building block for:
- Antiviral drug development
- Kinase inhibitor synthesis
- PET tracer manufacturing
Agrochemical Synthesis
Key component in production of:
- Herbicidal compounds
- Plant growth regulators
- Pesticide metabolites
3. Safety & Handling Protocols
| Hazard Class | Preventive Measures |
|---|---|
| Acute Toxicity (Oral, Category 5) | Use chemical-resistant gloves (≥0.11mm) NIOSH-approved respirator for powder handling |
| Eye Irritation (Category 2B) | ANSI Z87.1-compliant eye protection Emergency eyewash station within 10-second access |
First Aid Measures
- Eye Contact: Flush with lukewarm water ≥15 minutes using eyewash station
- Skin Contact: Remove contaminated clothing, wash with pH-neutral detergent
- Inhalation: Move to fresh air, monitor for respiratory distress
4. Regulatory Compliance
Customs Classification
| Region | HS Code | Description |
|---|---|---|
| European Union | 29333999 | Pyridine derivatives with unfused rings |
| United States | 2933391000 | Fluorinated pyridine carboxylic acids |
5. Technical Support & Inquiry
For analytical certificates, bulk pricing, or custom synthesis requirements:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request product documentation:
- Material Safety Data Sheet (ISO 11014-1:2023 compliant)
- Certificate of Analysis (HPLC ≥98.5% purity)
- Stability Studies (ICH Q1A guidelines)
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