(1R,2R)-1,2-Cyclohexanedimethanol

Product Name:(1R
2R)-1
2-Cyclohexanedimethanol
CAS:65376-05-8
MFC8H16O2
MW:144.21
EINECS:692-053-7
MOL File:65376-05-8.mol

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Comprehensive Guide to (1R,2R)-1,2-Cyclohexanedimethanol

Table of Contents

1. Product Overview & Specifications

(1R,2R)-1,2-Cyclohexanedimethanol (CAS 2615-79-0) is a chiral cyclohexane derivative widely used in high-performance polymers, pharmaceuticals, and optical materials. Below are key specifications:

Parameter Specification (1S,2S) Isomer Comparison
Molecular Formula C8H16O2 Same formula, different stereochemistry
Purity ≥99% (HPLC) ≥98%
Melting Point 78-82°C 75-80°C
Optical Rotation [α]D²⁰ = +15° to +18° (c=1, EtOH) [α]D²⁰ = -15° to -18°

2. Applications & Industry Use Cases

Key Industries Served:

  • Polymer Manufacturing: Enhances thermal stability in polyester resins for automotive coatings.
  • Pharmaceuticals: Chiral building block for antitumor agents and antiviral drugs.
  • Optical Materials: Improves refractive index in polycarbonate lenses.
  • Adhesives: Increases flexibility in epoxy-based systems.

3. Usage Guidelines & Best Practices

Handling Recommendations:

  • Store at 2-8°C in airtight containers under nitrogen.
  • Use PPE (gloves, goggles) during handling.
  • Incompatible with strong oxidizing agents.

4. Customer Case Studies

Case Study 1: High-Temperature Coatings Manufacturer

  • Challenge: Improve heat resistance of automotive clearcoats above 200°C.
  • Solution: 15% (1R,2R)-CHDM in polyester resin formulation.
  • Result: 40% longer lifespan under thermal cycling tests.

Case Study 2: Antiviral Drug Development

  • Challenge: Synthesize enantiopure nucleoside analogs.
  • Solution: Used as chiral auxiliary in asymmetric synthesis.
  • Result: Achieved 99.2% ee in final API intermediate.

5. Inquiry & Contact

Request custom formulations or bulk pricing:

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