Propylene Glycol Diethylhexanoate CAS 93981-97-6: Comprehensive Guide & Industry Applications (2025)
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Functional Advantages
- 3. Performance Comparison With Alternatives
- 4. Industrial Use Cases & Formulation Examples
- 5. Verified Client Success Stories
- 6. Technical Support & Customized Solutions
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | Propylene Glycol Diethylhexanoate |
| CAS Number | 93981-97-6 |
| Molecular Formula | C16H30O4 |
| Molecular Weight | 286.41 g/mol |
| Appearance | Clear colorless liquid |
| Solubility | Miscible with oils, ethanol; insoluble in water |
| Density (25°C) | 0.91-0.93 g/cm³ |
| Boiling Point | >200°C |
| Flash Point | >150°C |
| Primary Applications | Cosmetics, Pharmaceuticals, Lubricants, Plasticizers |
2. Key Applications & Functional Advantages
2.1 Cosmetic Formulations
As premium emollient with non-greasy texture:
- Enhances SPF product spreadability (UV filter compatibility)
- Improves moisturizer longevity on skin
- Reduces stickiness in hair care products
2.2 Pharmaceutical Uses
- Solubilizer for topical drug delivery systems
- Stabilizer for ointments/creams (pH 4-8 stable)
- Penetration enhancer for transdermal patches
2.3 Industrial Applications
- High-temperature lubricant additive
- Plasticizer for specialty polymers
- Metalworking fluid component
3. Performance Comparison With Alternatives
| Parameter | PG Diethylhexanoate | PG Monocaprylate | PG Dicaprylate/Dicaprate |
|---|---|---|---|
| Viscosity (25°C) | 12-15 mPa·s | 20-25 mPa·s | 18-22 mPa·s |
| Oxidative Stability | Excellent | Good | Moderate |
| Cold Resistance | -40°C stable | -20°C stable | -30°C stable |
| SPF Synergy | High | Medium | Low |
| FDA Approval Status | GRAS/EAFUS listed | Limited approval | Not approved |
4. Industrial Use Cases & Formulation Examples
4.1 Cosmetic Application: Long-lasting Moisturizer
Formula %:
- 5% PG Diethylhexanoate
- 8% Caprylic/Capric Triglyceride
- 3% Vitamin E Acetate
- 2% Hyaluronic Acid
Benefits: 24-hour hydration without oiliness
4.2 Pharmaceutical Use: Transdermal Analgesic Patch
- 15% Active ingredient
- 10% PG Diethylhexanoate (penetration enhancer)
- Polyacrylate adhesive matrix
Result: 40% faster drug absorption vs standard formulations
5. Verified Client Success Stories
5.1 Skincare Innovations Ltd. (UK)
- Challenge: Reformulate SPF50+ cream reducing white cast
- Solution: 7% PG Diethylhexanoate as primary emollient
- Outcome: 30% reduction in titanium dioxide content while maintaining SPF
5.2 PharmaHealth Solutions (USA)
- Requirement: Stabilize pH-sensitive topical antibiotic
- Implementation: 12% PG Diethylhexanoate in ointment base
- Result: 18-month shelf life extension at 25°C
6. Technical Support & Customized Solutions
Contact our chemical engineers for application-specific guidance:
Email: info@vivalr.com
Tel: (86) 15866781826
Request:
- Free technical datasheet (SDS/TDS)
- Customized formulation samples
- Regulatory compliance consultation



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