2-Bromo-5-chloropyridine

Product Name:2-Bromo-5-chloropyridine
CAS:40473-01-6
MFC5H3BrClN
MW:192.44
EINECS:251-228-4
MOL File:40473-01-6.mol

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2-Bromo-5-chloropyridine: Comprehensive User Guide

1. Product Specifications & Comparison

Parameter 2-Bromo-5-chloropyridine Common Alternatives
CAS Number 40473-01-6 N/A
Molecular Formula C5H3BrClN C5H3BrClN (isomers)
Molecular Weight 192.44 g/mol 192.44 g/mol (isomers)
Physical State Light brown to yellow crystalline powder Varies by isomer
Melting Point 65–69°C 59–61°C (e.g., 3-Bromo-2-chloropyridine)
Density 1.736 g/cm3 1.6–1.8 g/cm3 (typical for pyridine derivatives)

2. Applications

2-Bromo-5-chloropyridine is a halogenated pyridine derivative widely used in:

  • Pharmaceutical Intermediates: Key building block for synthesizing active pharmaceutical ingredients (APIs) targeting neurological and oncological diseases.
  • Agrochemicals: Precursor in herbicides and fungicides due to its stability under harsh conditions.
  • Material Science: Used in organic electronics and coordination chemistry for ligand design.
  • Research & Development: Critical for cross-coupling reactions (e.g., Suzuki-Miyaura) to create complex heterocyclic systems.

3. Usage Scenarios

Scenario 1: API Synthesis

Used in a palladium-catalyzed coupling reaction to produce a kinase inhibitor intermediate, achieving >95% yield under optimized conditions.

Scenario 2: Herbicide Formulation

Integrated into a pre-emergent herbicide formulation, demonstrating 98% weed suppression in field trials.

4. Customer Case Studies

Case Study 1: Shanghai Xinyu Biotechnology Co., Ltd.

Challenge: Required high-purity (>98%) 2-Bromo-5-chloropyridine for a novel antipsychotic drug synthesis.

Solution: Supplied 50 kg of material with HPLC-certified purity of 99.2%, enabling successful scale-up to Phase II clinical trials.

Case Study 2: European Agrochemical Innovator

Challenge: Needed a stable halogenated precursor for a next-generation fungicide.

Solution: Provided custom synthesis services to deliver 200 kg batches with consistent impurity profiles (<0.5%).

5. Contact Information

For technical specifications, bulk orders, or custom synthesis inquiries:

Email info@vivalr.com
Phone (86) 15866781826
Lead Time 2–4 weeks (standard orders)
6–8 weeks (custom synthesis)

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