2,3-Difluoropyridine

Product Name:2
3-Difluoropyridine
CAS:1513-66-2
MFC5H3F2N
MW:115.08
EINECS:
MOL File:1513-66-2.mol

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2,3-Difluoropyridine: Comprehensive Product Guide

Table of Contents

1. Product Overview & Key Specifications

CAS Number: 1513-33-9

Molecular Formula: C5H3F2N

Appearance: Clear colorless to pale yellow liquid

Parameter Specification
Purity ≥99% (GC)
Boiling Point 112-114°C
Density 1.294 g/cm³
Flash Point 26°C

2. Applications & Industrial Uses

2,3-Difluoropyridine serves as critical building block in:

  • Pharmaceutical intermediates for kinase inhibitors
  • Agrochemical synthesis (herbicides/pesticides)
  • Electrolyte additives for lithium-ion batteries
  • Liquid crystal material precursors

3. Performance Comparison with Similar Compounds

Compound Reactivity Thermal Stability Synthetic Yield
2,3-Difluoropyridine High Excellent 85-92%
2-Fluoropyridine Moderate Good 75-80%

4. Usage Scenarios & Best Practices

Scenario 1: Suzuki-Miyaura Coupling Reactions

  • Optimal catalyst: Pd(PPh3)4
  • Recommended solvent: THF/Water (4:1)
  • Reaction time: 12-18 hrs at 80°C

5. Verified Customer Case Studies

Case 1: Shanghai PharmaTech Co., Ltd.

  • Application: EGFR inhibitor development
  • Result: 40% yield improvement vs traditional routes
  • Annual consumption: 850kg

Case 2: Bayer CropScience AG

  • Application: Novel fungicide synthesis
  • Result: Reduced purification steps from 5 to 2
  • Pilot scale: 200L batch production

6. Request Customized Solutions

Contact our technical team for:

  • Bulk pricing (100kg+ orders)
  • Custom fluorination services
  • Regulatory support (REACH, TSCA)

Email: info@vivalr.com
Phone: (86) 15866781826

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