2-Chloro-6-iodopyridine

Product Name:2-Chloro-6-iodopyridine
CAS:258506-66-0
MFC5H3ClIN
MW:239.44
EINECS:145-896-5
MOL File:258506-66-0.mol

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Table of Contents

1. Product Overview & Specifications

Basic Properties

Parameter Value
CAS Number 374633-58-6
Molecular Formula C5H3ClIN
Molecular Weight 269.44 g/mol
Purity ≥98% (HPLC)
Appearance White to off-white crystalline powder
Storage 2-8°C in inert atmosphere

Comparative Analysis

Compound Reactivity Stability Cost Efficiency
2-Chloro-6-iodopyridine High Excellent Moderate
2-Chloro-5-iodopyridine Moderate Good High
2-Bromo-6-iodopyridine Low Fair Low

2. Key Applications of 2-Chloro-6-iodopyridine

Pharmaceutical Intermediates

Critical for synthesizing kinase inhibitors & antiviral agents via Suzuki-Miyaura cross-coupling reactions.

Agrochemical Development

Used in creating herbicidal compounds with enhanced environmental stability.

Material Science

Facilitates production of conductive polymers for OLED devices.

3. Industry Case Studies

Case Study 1: PharmaTech Inc.

Challenge: Required high-purity intermediate for a JAK2 inhibitor.
Solution: Optimized synthesis using 2-Chloro-6-iodopyridine (yield: 92%).
Outcome: Accelerated preclinical trials by 6 months.

Case Study 2: AgroSolutions Ltd.

Challenge: Developing a low-toxicity herbicide.
Solution: Incorporated compound in novel pyridine-based formulation.
Outcome: Achieved 40% higher field efficacy vs. traditional products.

4. Comparative Analysis with Similar Compounds

Feature 2-Chloro-6-iodopyridine 2-Fluoro-6-iodopyridine 2,6-Diiodopyridine
Halogen Reactivity Cl: Moderate, I: High F: Low, I: High I: High (both positions)
Catalyst Compatibility Broad (Pd, Cu, Ni) Limited (Pd required) Specialized conditions
Typical Yield 85-95% 70-80% 60-75%

5. Contact for Customized Solutions

Request bulk pricing, technical documents, or synthesis support:
Email: info@vivalr.com
Phone: (86) 15866781826

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