4-Phenylpiperidine: Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
Chemical Name: 4-Phenylpiperidine
CAS Number: 2167-77-1
Molecular Formula: C11H15N
Molecular Weight: 161.24 g/mol
Comparative Analysis of Commercial Suppliers
| Supplier | Purity | Price (USD/g) | Packaging |
|---|---|---|---|
| Supplier A | >98% | $50 | 1g, 5g, 10g |
| Supplier B | >95% | $45 | 5g, 25g |
| Supplier C | >99% | $55 | Custom batches |
2. Key Applications
Pharmaceutical Intermediates
Critical precursor for opioid analgesics (e.g., fentanyl analogs) and antidepressants due to its piperidine scaffold.
Organic Synthesis
Used in Buchwald-Hartwig amination, reductive amination, and heterocycle construction for complex molecule assembly.
Catalyst Development
Employed as chiral ligands in asymmetric catalysis for enantioselective synthesis.
3. Industrial Use Cases
Case 1: Fentanyl Analog Synthesis
Process: N-alkylation of 4-phenylpiperidine with phenethyl bromide (Yield: 82%, Purity: 99.2%)
Case 2: Antidepressant Development
Process: Reductive amination with 2-naphthoyl chloride (IC50: 12nM on SERT)
4. Client Success Stories
PharmaTech Inc (USA)
Application: Developed novel COX-2 inhibitor using 4-phenylpiperidine intermediate
Result: 40% reduction in synthesis steps vs traditional routes
BioSynth Co (Germany)
Application: Scaled-up production of SSRI drug candidates
Result: Achieved 500kg/month production with >99.5% HPLC purity
5. Request Custom Quotes
Contact our technical team for bulk pricing, regulatory documentation (CoA, MSDS), and custom synthesis options:
Email: info@vivalr.com
Phone: (86) 15866781826
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