2-Chloro-5-nitropyridine

Product Name:2-Chloro-5-nitropyridine
CAS:4548-45-2
MFC5H3ClN2O2
MW:158.54
EINECS:224-908-3
MOL File:4548-45-2.mol

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2-Chloro-5-nitropyridine: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

CAS Number: 4585-45-3

Molecular Formula: C5H3ClN2O2

Molecular Weight: 174.55 g/mol

Appearance: Light yellow crystalline powder

Purity: ≥98% (HPLC)

Storage: 2-8°C in airtight container

2. Key Applications & Industry Uses

Widely used as intermediate in:

  • Pharmaceutical synthesis (HIV protease inhibitors)
  • Agrochemical production (herbicides/pesticides)
  • Electron-deficient pyridine derivatives
  • Cross-coupling reactions

3. Technical Parameter Comparison

Parameter Standard Grade High Purity Grade
Purity ≥98% ≥99.5%
Moisture Content <0.5% <0.1%
Package Size 1kg-25kg 100g-5kg

4. Operational Guidelines & Safety

Handling Precautions:

  • Use nitrile gloves & chemical goggles
  • Avoid inhalation of dust
  • Incompatible with strong oxidizers

Reaction Conditions:

  • Typical reaction temp: 80-120°C
  • Recommended solvents: DMF, THF

5. Real-World Use Cases

Case 1: Pharmaceutical Intermediate Synthesis

A European pharma company used 4585-45-3 in 6-step synthesis of antiviral drug candidate:

  • Yield improvement: 72% → 89%
  • Purity level: API grade (99.92%)

Case 2: Agrochemical Manufacturing

Chinese agrochemical producer achieved:

  • 30% cost reduction in pesticide production
  • Batch consistency: RSD <1.5%

6. Request Quote/Samples

Customization Available:

  • Bulk quantities (25kg+ drum packaging)
  • GMP-grade manufacturing
  • Technical documentation support

Contact our chemical specialists:

Email: info@vivalr.com
Phone: (86) 15866781826

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