1. Product Overview & Specifications

6-Chloropyrimidin-4(3H)-one (CAS: 4765-77-9) is a pale-yellow crystalline powder widely used as a pharmaceutical intermediate and organic synthesis reagent. Key specifications include:

Comparative Advantages: Compared to similar intermediates, it offers higher thermal stability (melting point: 108–112°C) and solubility in polar solvents like water and ethanol, making it ideal for scalable synthesis.

2. Key Applications

This compound serves critical roles in:

• Pharmaceutical Synthesis: Intermediate for antiviral and anticancer drugs (e.g., kinase inhibitors).
• Agrochemicals: Precursor for herbicides and fungicides.
• Research & Development: Building block in heterocyclic chemistry for novel compound discovery.

3. Usage Scenarios

Example 1: In API synthesis, 6-Chloropyrimidin-4(3H)-one is alkylated at the 4-position to create nucleoside analogs for antiviral therapies.

Example 2: Used in cross-coupling reactions (e.g., Suzuki-Miyaura) to introduce functional groups for targeted drug delivery systems.

4. Client Case Studies

Case Study 1: Korean Pharmaceutical Manufacturer

A leading Seoul-based company integrated this compound into their production of a tyrosine kinase inhibitor, reducing synthesis steps by 20% and improving yield consistency.

Case Study 2: Chinese Biotech Firm

Jiangsu BioTech utilized 6-Chloropyrimidin-4(3H)-one to develop a novel antifungal agent, achieving 99.5% purity in final API batches.

5. Contact for Inquiries

For technical specifications, bulk pricing, or custom synthesis options:

Email: info@vivalr.com

Tel: (86) 15866781826