Comprehensive Guide to 4-Chloro-5-iodopyrimidine
Table of Contents
1. Product Overview & Specifications
| Parameter | 4-Chloro-5-iodopyrimidine | Similar Compounds |
|---|---|---|
| CAS Number | 1072-91-5 | 4-Chloro-6-iodopyrimidine: 89471-43-4 |
| Molecular Formula | C4H2ClIN2 | Varies by isomer |
| Purity | ≥98% (HPLC) | Typically 95-99% |
| Storage | 2-8°C in dark | Similar requirements |
2. Key Applications
Pharmaceutical Intermediates
Critical building block for:
- Kinase inhibitors (e.g., anticancer drugs)
- Antiviral compound synthesis
- PET radiopharmaceutical precursors
Agrochemical Development
- Herbicide intermediate with enhanced selectivity
- Fungicide molecular backbone modification
3. Usage Guidelines
Handling Protocols
- Use under inert atmosphere (N2 or Ar)
- Compatible with Suzuki coupling reactions
- Recommended solvent: Dry DMF or THF
4. Industry Case Studies
Case Study 1: Oncology Drug Development
Client: Top 10 Global Pharma Company
Application: Synthesis of Bruton’s tyrosine kinase (BTK) inhibitor intermediate
Result: Achieved 92% yield in key coupling reaction
Case Study 2: Advanced Material Research
Client: EU-based Research Institute
Application: OLED material precursor development
Result: Enhanced electron mobility by 40%
5. Request Customized Solutions
Contact our technical team for:
- Bulk pricing (100g to ton-scale)
- Custom synthesis options
- Regulatory support (REACH, TSCA)
Email: info@vivalr.com
Tel: (86) 15866781826
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